190187-44-1

Upstream product

• 139091-30-8 (S)-benzyl (1-(indol-3-yl)-3-oxopropan-2-yl)carbamate 
• 5241-58-7 L-Phenylalanine amide 
• 190187-38-3 [(1S,2R)-2-((S)-1-Carbamoyl-2-phenyl-ethylamino)-2-cyano-1-(1H-indol-3-ylmethyl)-ethyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Pseudopeptide CCK-4 analogues incorporating the Ψ[CH(CN)NH] peptide bond surrogate

The synthesis, binding to CCK receptors, and in vitro functional activity of pseudopeptide CCK-4 analogues incorporating the (R) or (S) Ψ[CH(CN)NH] peptide bond surrogate at the Nle31-Asp32 or Trp30-Nle31 bonds are described. Z-TrpΨ[(S)CH(CN)NH]Nle-Asp-Phe-NH2 retained the high CCK-B receptor binding affinity of Boc-[Nle31]-CCK-4, and was a potent and selective CCK-B antagonist in the isolated guinea pig ileum.