190206-05-4

Basic information

• Product Name: 1-(4-mercapto-1-phenylbutyl)-1-cyclopentanol
• Synonyms: 1-(4-mercapto-1-phenylbutyl)-1-cyclopentanol
• CAS NO: 190206-05-4
• Molecular Weight: 250.405
• Mol File: 190206-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-mercapto-1-phenylbutyl)-1-cyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-mercapto-1-phenylbutyl)-1-cyclopentanol(190206-05-4)
• EPA Substance Registry System: 1-(4-mercapto-1-phenylbutyl)-1-cyclopentanol(190206-05-4)

Safety Data

• Hazardous Substances Data: 190206-05-4(Hazardous Substances Data)

Upstream product

• 2060-65-3 2-phenyl tetrahydro thiophene 
• 120-92-3 cyclopentanone 
• 939-52-6 4-chloro-1-phenylbutan-1-one 
• 33553-82-1 4-chloro-1-phenyl-1-butanol 

Relevant articles and documents

Reductive opening of phenyl substituted thiacycloalkanes: New way for sulphur-containing organolithium compounds

The reaction of 2-phenyl substituted four, five and six membered thiacycloalkanes (1, 4 and 7) with lithium and a catalytic amount of DTBB (5 mol %) in THF at -78°C leads to the corresponding sulphur-containing benzylic organolithium compounds (2, 5 and 8), which by reaction with different electrophiles [D2O, Me3SiCl, Bu(t)CHO, Me2CO, Et2CO, (CH2)4CO, CO2] followed by hydrolysis with water afford the expected functionalised mercaptans (3, 6 and 9) in a regioselective manner. Some reaction products (3, 6) are cyclised under acidic conditions (85% phosphoric acid) to yield the corresponding homologous substituted sulphur-containing saturated heterocycles (10, 11).