19026-22-3

Basic information

• Product Name: 2-acetamido-2-deoxy-D-glucono-.delta.-lactone
• Synonyms: 2-acetamido-2-deoxy-D-glucono-.delta.-lactone;2-Acetylamino-2-deoxy-D-gluconic acid δ-lactone;CD-80110;Einecs 242-761-3;N-Acetyl-D-glucosamino-1,5-lactone, 2-Acetamido-2-deoxy-D-gluconolactone;2-AcetaMido-2-deoxy-D-gluconolactone;N-AcetylglucosaMino-1,5-lactone
• CAS NO: 19026-22-3
• Molecular Formula: C₈H₁₃NO₆
• Molecular Weight: 219.19192
• EINECS: 242-761-3
• Product Categories: 13C & 2H Sugars;Carbohydrates & Derivatives
• Mol File: 19026-22-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 168-170°C
• Boiling Point: 602 °C at 760 mmHg
• Flash Point: 317.9 °C
• Appearance: White Crystalline Solid
• Density: 1.5 g/cm³
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
• Stability: Hygroscopic
• CAS DataBase Reference: 2-acetamido-2-deoxy-D-glucono-.delta.-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetamido-2-deoxy-D-glucono-.delta.-lactone(19026-22-3)
• EPA Substance Registry System: 2-acetamido-2-deoxy-D-glucono-.delta.-lactone(19026-22-3)

Safety Data

• Hazardous Substances Data: 19026-22-3(Hazardous Substances Data)

Usage

Chemical Properties

2-acetamido-2-deoxy-D-glucono-.delta.-lactone is white Crystalline Solid

Uses

2-acetamido-2-deoxy-D-glucono-.delta.-lactone is used to inhibit breakdown of products by beta-hexosaminidase(s) when the culture medium is used as an enzyme source

Upstream product

• 14131-68-1 N-acetyl-D-glucosamine 

Relevant articles and documents

Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen

Discovery of novel enzymes is a challenging task, yet a crucial one, due to their increasing relevance as chemical catalysts and biotechnological tools. In our work we present a high-throughput screening approach to discovering novel activities. A screen of 96 putative oxidases with 23 substrates led to the discovery of two new enzymes. The first enzyme, N-acetyl-D-hexosamine oxidase (EC 1.1.3.29) from Ralstonia solanacearum, is a vanillyl alcohol oxidase-like flavoprotein displaying the highest activity with N-acetylglucosamine and N-acetylgalactosamine. Before our discovery of the enzyme, its activity was an orphan one - experimentally characterized but lacking the link to amino acid sequence. The second enzyme, from an uncultured marine euryarchaeota, is a long-chain alcohol oxidase (LCAO, EC 1.1.3.20) active with a range of fatty alcohols, with 1-dodecanol being the preferred substrate. The enzyme displays no sequence similarity to previously characterised LCAOs, and thus is a completely novel representative of a protein with such activity.