190273-70-2 Usage
Uses
Used in Pharmaceutical Industry:
2-Amino-5-chloroquinazoline is utilized as a building block for the synthesis of various biologically active compounds, playing a crucial role in the development of new drugs.
Used in Cancer Treatment:
In the field of oncology, 2-Amino-5-chloroquinazoline is studied for its potential therapeutic use against cancer, highlighting its capacity to contribute to the treatment of various types of malignancies.
Used in Antimicrobial Applications:
2-Amino-5-chloroquinazoline is employed as an antimicrobial agent, leveraging its properties to combat bacterial infections, making it a valuable component in the development of new antimicrobial drugs.
Used in Antifungal Applications:
Similarly, 2-Amino-5-chloroquinazoline is used as an antifungal agent, indicating its potential to be incorporated into treatments for fungal infections.
Used in Materials Science:
2-Amino-5-chloroquinazoline is also researched for its potential applications in materials science, where it may contribute to the creation of novel materials with specific properties.
Used as an Antioxidant:
Furthermore, 2-Amino-5-chloroquinazoline has been studied for its antioxidant properties, suggesting its use in applications requiring the prevention of oxidative damage, such as in the food industry or in cosmetic products.
Check Digit Verification of cas no
The CAS Registry Mumber 190273-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,2,7 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 190273-70:
(8*1)+(7*9)+(6*0)+(5*2)+(4*7)+(3*3)+(2*7)+(1*0)=132
132 % 10 = 2
So 190273-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClN3/c9-6-2-1-3-7-5(6)4-11-8(10)12-7/h1-4H,(H2,10,11,12)
190273-70-2Relevant academic research and scientific papers
NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS
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Page/Page column 185, (2011/12/02)
Unsaturated nitrogen heterocyclic compounds of formula (I): (I), as defined in the specification, compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, Huntington's Disease, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Synthesis of 2-Aminoquinazolines from ortho-Fluorobenzaldehydes
Hynes, John B.,Campbell, Johnny P.
, p. 385 - 387 (2007/10/03)
The reaction of guanidine carbonate with various ortho-fluorobenzaldehydes in N,N-dimethylacetamide was investigated as a potential route for preparing 2-aminoquinazolines. Eleven new 2-aminoquinazolines were elaborated in this manner in low to moderate yields. In general the best results were obtained with ortho-fluorobenzaldehydes possessing an electron withdrawing substituent at the other ortho position. Complex mixtures were obtained using 2-fluorobenzaldehyde, 2,5-difluorobenzaldehyde and 2-fluoro-5-methoxybenzaldehyde which were not resolved.
