190273-85-9 Usage
Physical properties
white or light yellow solid, insoluble in water, soluble in organic solvents
Primary use
pharmaceutical research and development
Quinazoline ring structure
Amino and difluoro substituents
Unique pharmacological properties
Potential applications in materials science
Precursor for synthesis of other organic compounds
Important and versatile chemical with implications in various scientific and industrial fields
Check Digit Verification of cas no
The CAS Registry Mumber 190273-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,2,7 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 190273-85:
(8*1)+(7*9)+(6*0)+(5*2)+(4*7)+(3*3)+(2*8)+(1*5)=139
139 % 10 = 9
So 190273-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F2N3/c9-5-1-2-6-4(7(5)10)3-12-8(11)13-6/h1-3H,(H2,11,12,13)
190273-85-9Relevant academic research and scientific papers
Synthesis of 2-Aminoquinazolines from ortho-Fluorobenzaldehydes
Hynes, John B.,Campbell, Johnny P.
, p. 385 - 387 (2007/10/03)
The reaction of guanidine carbonate with various ortho-fluorobenzaldehydes in N,N-dimethylacetamide was investigated as a potential route for preparing 2-aminoquinazolines. Eleven new 2-aminoquinazolines were elaborated in this manner in low to moderate yields. In general the best results were obtained with ortho-fluorobenzaldehydes possessing an electron withdrawing substituent at the other ortho position. Complex mixtures were obtained using 2-fluorobenzaldehyde, 2,5-difluorobenzaldehyde and 2-fluoro-5-methoxybenzaldehyde which were not resolved.
