1902955-29-6

Basic information

• Product Name: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
• CAS NO: 1902955-29-6
• Molecular Weight: 267.232
• Mol File: 1902955-29-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 409.4±45.0 °C(Predicted)
• Density: 1.314±0.06 g/cm3(Predicted)
• CAS DataBase Reference: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate(1902955-29-6)
• EPA Substance Registry System: methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate(1902955-29-6)

Safety Data

• Hazardous Substances Data: 1902955-29-6(Hazardous Substances Data)

Usage

General Description

Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate is a chemical compound with a molecular formula C13H10F2NO3. It is a pyrrole derivative that contains a 2,4-difluorophenyl group and a methoxy group. methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate is often used in organic synthesis and medicinal chemistry as a building block for the construction of various biologically active molecules. Its unique structure and functional groups make it valuable for the development of new drugs and pharmaceutical compounds. Additionally, it has potential applications in the fields of agrochemicals, materials science, and dyes due to its versatility in chemical reactions and synthetic pathways.

Upstream product

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Relevant articles and documents

Method for preparing potassium ion competitive retardant intermediate

The invention discloses a method for synthesizing a key intermediate compound 1 of a novel potassium ion competitive retardant fexuprazan, and belongs to the field of synthesis of medical intermediates. The invention aims to solve the problems of high preparation cost, low yield and the like of the compound 1, further improve the productivity and reduce the production cost. According to the method, 2, 4-difluorobenzylamine is used as a raw material, and a target product is obtained through condensation reaction, benzyl protection, cyclization under an alkaline condition, methylation, deprotection and the like in sequence. According to the method for synthesizing the compound 1, a novel process route is adopted, the yield is larger than 50%, and the method has the advantages of being novelin route, mild in reaction condition, low in cost and the like.

METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE

The present invention relates to a.method for preparing intermediates of 4- methoxypyrrole derivatives. The preparation method according to the present invention has advantages that the production cost can be lowered by using inexpensive starting materials, a high-temperature reaction is not required as a whole, inexpensive and non-explosive reagents are used instead of (trimethylsilyl)diazomethane, and further an intermediate of 4-methoxypyrrole derivatives can be prepared as a whole at a high yield.

NOVEL ACID ADDITION SALT OF 1-(5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-1H-PYRROL-3-YL)-N-METHYLMETHANAMINE

The present invention provides a novel acid addition salt of 1-(5-(2,4-difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine. The acid addition salt has excellent proton pump inhibitory activity, gastric damaging activity and defense factor enhancing effect, and has excellent Helicobacter pylori (H. pylori) eradication activity to be usefully used in prevention and treatment of gastrointestinal tract, ulcers, gastritis, reflux esophagitis, or gastrointestinal damages by H. pylori.COPYRIGHT KIPO 2017