19031-42-6

Basic information

• Product Name: 5-Quinoxalinamine,2-methyl-(9CI)
• Synonyms: 5-Quinoxalinamine,2-methyl-(9CI);2-Methylquinoxalin-5-amine;2-Methyl-5-quinoxalinamine
• CAS NO: 19031-42-6
• Molecular Formula: C9H9N3
• Molecular Weight: 159.18786
• Product Categories: QUINOXALINE
• Mol File: 19031-42-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Quinoxalinamine,2-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Quinoxalinamine,2-methyl-(9CI)(19031-42-6)
• EPA Substance Registry System: 5-Quinoxalinamine,2-methyl-(9CI)(19031-42-6)

Safety Data

• Hazardous Substances Data: 19031-42-6(Hazardous Substances Data)

Upstream product

• 76982-28-0 2-methyl-5-nitroquinoxaline 
• 497-19-8 sodium carbonate 
• 3694-52-8 2,3-diamino-nitrobenzene 

Relevant articles and documents

FIBROSIS INHIBITOR

Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I): wherein Ring Z is optionally substituted pyrrole ring, etc.; W2 is -CO-, -SO2-, optionally substituted C1-C4 alkylene, etc.; Ar2 is optionally substituted aryl, etc.; W1 and Ar1 mean the following (1) and (2):(1) W1 is optionally substituted C1-C4 alkylene, etc.; Ar1 is optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms:(2) W1 is optionally substituted C2-C5 alkylene, optionally substituted C2-C5 alkenylene, etc.; and Ar1 is aryl or monocyclic heteroaryl, which is substituted by carboxyl, alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof.

A Method for the Regioselective Synthesis of 2-Methyl-5-nitro- and 2-Methyl-8-nitroquinoxalines, and the Application of Proton-Coupled 13C NMR to Assign their Structure

The regioselective synthesis of the title compounds and some of their bromo and chloro derivatives from the condensation of 3-nitro-1,2-benzenediamines with methylglyoxal (pyruvic aldehyde) is described.The splitting patterns at the bridgehead carbons in the proton-coupled 13C NMR spectra are proposed as a useful method for the distinction of the isomers formed after such a condensation.The previously reported erroneous structures of 5-amino, 5-bromo- and 5-chloro-2-methylquinoxalines are corrected.