190331-35-2Relevant academic research and scientific papers
INHIBITORS OF AMYLOID BETA-PROTEIN PRODUCTION
-
, (2008/06/13)
A method of protecting a warm-blooded mammal from the progression of Alzheimer"s disease, which comprises administering an effective amount of a compound of general formula.
CHEMICAL COMPOUNDS AS INHIBITORS OF AMYLOID BETA PROTEIN PRODUCTION
-
, (2008/06/13)
A compound of the formula I in which Z is O or S; R11 is a halogen atom; R12 is a halogen atom or a trifluoromethyl group; and X is S, SO, SO2, O or NH; R4 is naphthyl, quinolinyl, benzimidazolyl, pyridyl, pyradazinyl, benzoxazolyl or benzothiazolyl, unsubstituted or substituted by one or two substituents selected from a halogen atom, (1-4C)alkyl, (1-4C)alkoxy, nitro, (1-4C)alkoxycarbonyl, halo(1-4C)alkyl, and phenyl; or a pharmaceutically acceptable salt thereof. The compounds are useful as inhibitors of amyloid beta-protein production.
