190365-96-9

Basic information

• Product Name: 2-Benzothiazoleethanethioamide(9CI)
• Synonyms: 2-Benzothiazoleethanethioamide(9CI);2-Benzothiazol-2-yl-thioacetamide
• CAS NO: 190365-96-9
• Molecular Formula: C₉H₈N₂S₂
• Molecular Weight: 208.3
• Product Categories: BENZOTHIAZOLE
• Mol File: 190365-96-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Benzothiazoleethanethioamide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazoleethanethioamide(9CI)(190365-96-9)
• EPA Substance Registry System: 2-Benzothiazoleethanethioamide(9CI)(190365-96-9)

Safety Data

• Hazardous Substances Data: 190365-96-9(Hazardous Substances Data)

Upstream product

• 56278-50-3 2-cyanomethylbenzothiazole 
• 62-55-5 thioacetamide 
• 137-07-5 2-amino-benzenethiol 
• 29182-42-1 ethyl 2-(2-benzothiazolyl)acetate 
• 51542-41-7 2-(1,3-benzothiazol-2-yl)ethanamide 

Downstream Products

• 218794-44-6 2-amino-5-(1,3-benzothiazol-2-yl)-4-(4-methoxyphenyl)-6-thiono-1,6-dihydropyridine-3-carbonitrile 
• 218794-38-8 2-amino-5-(1,3-benzothiazol-2-yl)-4-phenyl-6-thiono-1,6-dihydropyridine-3-carbonitrile 
• 218794-41-3 2-amino-5-(1,3-benzothiazol-2-yl)-4-(4-chlorophenyl)-6-thiono-1,6-dihydropyridine-3-carbonitrile 
• 218794-32-2 (E)-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)prop-2-enethioamide 
• 218794-30-0 (E)-2-(1,3-benzothiazol-2-yl)-3-phenylprop-2-enethioamide 
• 218794-35-5 (E)-2-(1,3-benzothiazol-2-yl)-3-(4-methoxyphenyl)prop-2-enethioamide 
• 1032-98-0 3-(benzothiazol-2-yl)coumarin 
• 218794-19-5 2-<1,3-benzothiazol-2-yl<(E)-2-phenylhydrazono>methyl>-1,3-thiazol-4(5H)-one 
• 1214990-24-5 2-[(4-phenyl-1,3-thiazol-2-yl)methyl]-1,3-benzothiazole 

Relevant articles and documents

Metal chelation aptitudes of bis(o-azaheteroaryl)methanes as tuned by heterocycle charge demands

We describe the synthesis of a number of 1,3-azol-2-yl-, 1,3-benzazol-2-yl-, and azinyl-based bis- (o-azaheteroaryl)methanes (LH, L- = Het2CH-) and their coordinating properties toward divalent transition metals (Zn, Cu, Co, Ni, Hg,

Some reactions of 2-cyanomethyl-1,3-benzothiazole with expected biological activity

New pyrido[2,1-b]benzothiazoles 2a,b, 3, 2-aminoquinoline 4, coumarin 5, cyclohexane 6a,b, and 2-(1,3-benzothiazol-2-yl) methylidene 7 derivatives have been prepared via the reaction of 2-cyanomethyl-1,3-benzothiazole 1 with ,-unsaturated nitriles, α-chloro ethyl acetoacetate, 2-amino benzaldehyde, 5-chlorosalicylaldehyde, α,β-unsaturated ketone, and 2-aminobenzothiol hydrochloride. 2-Thiazole derivatives 9a,b were prepared from compound 1, which was converted to thioamide derivative 8 by reaction with HCl and thioacetamide, and cyclization of this thioamide with α-halogenated ketone gave 9a,b. Reaction of compound 1 and ethylacetate to afford ketonitrile 10. Treatment of 10 with hydrazine hydrate afforded aminopyrazole derivative 11. Substituted 4-aminothiophene 13 has been synthesized by reaction of compound 1 with p-chlorophenyl isothiocyanate. The resulting product 12 was then alkylated with phenacylbromide. Phenyl-2-yl-carbonylhydroximoyl-chloride 15 was prepared by treatment of the corresponding sulfonium bromide with sodium nitrite and hydrochloric acid in dioxane. Compound 15 reacted with α-(1,3- benzothiazol-2-yl) cinnamonitrile 14 afforded the isoxazole derivatives 16. Reaction of coumarin derivative 5 with anthranilamide, pyrimidine diamine, thiosemicarbazide, acetylacetone, and hydrazine hydrate yielded quinazoline-2-one 17, purine 18, triazole 19, 2-acetyl naphthalene-2-one 20, and N-aminoquinoline-2-one 21 derivatives.

(Benzothiazole-2-yl)(4-methylthiazole-2-yl)methane, and (Benzothiazole-2-yl)(4-methylthiazole-2-yl)ketone oxime, New Polyfunctional Bishetarylmethanes

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