19040-67-6 Usage
Uses
Used in Pharmaceutical Industry:
7,8-Dihydroxy-4-propylcoumarin is used as a therapeutic agent for the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Its potential therapeutic effects have been demonstrated in various studies, making it a promising candidate for further research and development.
Used in Antimicrobial Applications:
7,8-Dihydroxy-4-propylcoumarin is used as an antimicrobial agent due to its broad-spectrum activity against various microorganisms. Its ability to inhibit the growth of bacteria and fungi makes it a valuable compound for the development of new antimicrobial drugs.
Used in Anticancer Applications:
7,8-Dihydroxy-4-propylcoumarin is used as an anticancer agent, exhibiting potential cytotoxic effects on various cancer cell lines. Its ability to induce apoptosis and inhibit cell proliferation makes it a promising candidate for the development of novel cancer therapies.
Used in Hepatoprotective Applications:
7,8-Dihydroxy-4-propylcoumarin is used as a hepatoprotective agent, demonstrating potential protective effects on liver cells and reducing liver damage caused by various toxins and diseases. Its hepatoprotective properties make it a valuable compound for the development of liver-protecting drugs.
Used in Traditional Medicine:
7,8-Dihydroxy-4-propylcoumarin is used in traditional medicine for its anti-inflammatory, anticoagulant, and antioxidant properties. Its wide range of pharmacological activities makes it a valuable component in the development of natural remedies and herbal formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 19040-67-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,4 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19040-67:
(7*1)+(6*9)+(5*0)+(4*4)+(3*0)+(2*6)+(1*7)=96
96 % 10 = 6
So 19040-67-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H12O4/c1-2-3-7-6-10(14)16-12-8(7)4-5-9(13)11(12)15/h4-6,13,15H,2-3H2,1H3
19040-67-6Relevant academic research and scientific papers
Preparation and pharmacological effects of coumarin derivative and application of coumarin derivative to treatment on pruritus
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Paragraph 0106; 0107; 0108, (2016/11/17)
The invention relates to preparation of a coumarin derivative 7,8-dihydroxy-4-trifluoromethyl-chromene-2H-chromen-2-one for treating the pruritus symptom, studies of pharmacodynamics on the aspects of a molecular pharmacology mechanism, a pruritus animal model and the like of the coumarin derivative, and a pharmaceutics study applicable to treatment on pruritus. The active compound is definite in pharmacological effect mechanism, is broad-spectrum and effective to treat the pruritus symptom, and can be used for clinical application to treatment on skin diseases.
The synthesis of novel crown ethers, part X*, 4-propyl-and 3-ethyl-4-methylchromenone-crown ethers
Tiftikci, Esra,Erk, Cakil
, p. 867 - 871 (2007/10/03)
Starting from ethyl propionylacetate, and ethyl 2-ethylacetoacetate we prepared 4-propyl-7,8-, 4-propyl-6,7-, 3-ethyl-4-methyl-7,8- and 3-ethyl-4-methyl-6,7-dihydroxy-2H-chromenones which were allowed to react with the bis-dihalides or ditosylates of glycols in DMF/Na2CO3 to afford the 6,7- and 7,8-chromenone derivatives of 12-crown-4, 15-crown-4 and 18-crown-6. The products were identified using ir, 13C and 1H nmr, ms and high resolution mass spectroscopy. The cation selectivities of chromenone crown ethers with Li+, Na+ and K+ cations were estimated from the steady state emission fluorescence spectra of free and cation complexed chromenone macrocyclic ethers in acetonitrile.
