19044-88-3 Usage
Chemical Properties
Yelloworange crystalline solid or powder.
Odorless.
Uses
Herbicide.
Definition
ChEBI: A sulfonamide that is benzenesulfonamide substituted at positions 3 and 5 by nitro groups and at position 4 by a dipropylamino group.
General Description
Yellow-orange crystals. Non corrosive. Used as an herbicide.
Agricultural Uses
Herbicide: Oryzalin is used to control annual grasses, herbaceous
plants, woody shrubs, vines and broadleaf weeds
on fruit and nut trees, soya beans, peas, sweet potatoes,
berries, vine and crops, cotton, Christmas tree plantations,
commercial/industrial and recreation area lawns, golf
course turf, residential lawns and turf, ornamental and/or
shade trees, nonagricultural rights-of-way, nonagricultural
uncultivated and industrial areas, power stations, paths/patios
and paved areas.
Trade name
AGVALUE?; COMPOUND 67019?;
DIRIMAL?; EL-119?; EXCEL-S-PLUS?; EXPEDITE?;
FLEXLAN?; NATIONS AG II?; ORYZA?; PRO-TECK?;
ROUT?; RYCELAN?; RYZELAN?; SNAPSHOT?;
SURFLAN?; TURF FERTILIZER?; XL 2G?
Safety Profile
Low toxicity by ingestion and skin contact. Mutation data reported. When heated to decomposition emits toxic fumes of NOx, SOx.
Potential Exposure
Oryzalin is a 2,6-dinitroaniline herbicide
used to control annual grasses, herbaceous plants,
woody shrubs, vines, and broad leaf weeds on fruit and nut
trees, soya beans, peas, sweet potatoes, berries, vine and
crops, cotton, Christmas tree plantations, commercial/industrial
and recreation area lawns, golf course turf, residential
lawns and turf, ornamental, and/or shade trees, nonagricultural
rights-of-way, nonagricultural uncultivated and industrial
areas, power stations, paths/patios, and paved areas.
Shipping
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneoushazardous
material, Technical Name Required. UN1596 Dinotoanilines,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Waste Disposal
Do not discharge into drains
or sewers. Dispose of waste material as hazardous waste
using a licensed disposal contractor to an approved landfill.
Consult with environmental regulatory agencies for guidance
on acceptable disposal practices. Incineration with
effluent gas scrubbing is recommended. Containers must be
disposed of properly by following package label directions
or by contacting your local or federal environmental control
agency, or by contacting your regional EPA office.
Check Digit Verification of cas no
The CAS Registry Mumber 19044-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,4 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19044-88:
(7*1)+(6*9)+(5*0)+(4*4)+(3*4)+(2*8)+(1*8)=113
113 % 10 = 3
So 19044-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)
19044-88-3Relevant articles and documents
Synthesis and evaluation of oryzalin analogs against Toxoplasma gondii
Endeshaw, Molla M.,Li, Catherine,Leon, Jessica De,Yao, Ni,Latibeaudiere, Kirk,Premalatha, Kokku,Morrissette, Naomi,Werbovetz, Karl A.
scheme or table, p. 5179 - 5183 (2010/10/03)
The synthesis and evaluation of 20 dinitroanilines and related compounds against the obligate intracellular parasite Toxoplasma gondii is reported. Using in vitro cultures of parasites in human fibroblasts, we determined that most of these compounds selectively disrupted Toxoplasma microtubules, and several displayed sub-micromolar potency against the parasite. The most potent compound was N1,N1-dipropyl-2,6-dinitro-4-(trifluoromethyl)-1,3- benzenediamine (18b), which displayed an IC50 value of 36 nM against intracellular T. gondii. Based on these data and another recent report [Ma, C.; Tran, J.; Gu, F.; Ochoa, R.; Li, C.; Sept, D.; Werbovetz, K.; Morrissette, N. Antimicrob. Agents Chemother. 2010, 54, 1453], an antimitotic structure-activity relationship for dinitroanilines versus Toxoplasma is presented.
Antileishmanial dinitroaniline sulfonamides with activity against parasite tubulin.
Bhattacharya, Gautam,Salem, Manar M,Werbovetz, Karl A
, p. 2395 - 2398 (2007/10/03)
Novel dinitroaniline sulfonamides based on the herbicide oryzalin 3 were synthesized and evaluated for activity against the parasitic protozoan Leishmania donovani and against leishmanial tubulin, the putative antiparasitic target of oryzalin. A subset of these compounds possess more activity against both Leishmania and the target protein in vitro. Compound 20 displays improved potency against leishmanial tubulin and is 13.4-fold more active against L. donovani axenic amastigotes than oryzalin.
5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides
-
, (2008/06/13)
5,6-Dihydro-1,2,4,6-thiatriazin-5-one-1,1-dioxides of the formula STR1 where R1 is hydrogen, a metal atom or an unsubstituted or substituted ammonium radical, R2 is a saturated or unsaturated straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical or 3 to 7 carbon atoms, a branched saturated or unsaturated aliphatic radical of 3 to 10 carbon atoms, a halogen-, alkoxy- or alkylmercapto-substituted aliphatic radical of 2 to 10 carbon atoms tetrahydrofuryl substituted methyl, a cycloalkoxy-substituted aliphatic radical of 4 to 10 carbon atoms, unsubstituted or halogen-substituted benzyl or phenyl, halophenyl, or alkylphenyl of a total of up to 10 carbon atoms, R3 is hydrogen, a straight-chain aliphatic radical of up to 10 carbon atoms, a cycloaliphatic radical of 3 to 7 carbon atoms, a branched aliphatic radical of 3 to 10 carbon atoms, haloalkyl, or alkoxyalkyl of 2 to 10 carbon atoms and X is oxygen and may also be sulfur if R2 is unsubstituted or halogen-substituted benzyl, processes for their preparation, and herbicides containing the above compounds.
