190518-89-9 Usage
Uses
Used in Organic Chemistry Research:
9H-Carbazole, 9-[1-(1-naphthalenylmethylene)-3-phenyl-2-propenyl]-, (Z,E)is used as a research compound in organic chemistry for its unique structure and potential reactivity. Its complex molecular arrangement allows chemists to explore new synthetic pathways and reactions, contributing to the advancement of organic chemistry.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 9H-Carbazole, 9-[1-(1-naphthalenylmethylene)-3-phenyl-2-propenyl]-, (Z,E)is utilized as a starting material or intermediate in the synthesis of new pharmaceutical agents. Its structural features may offer novel biological activities, making it a valuable component in the development of innovative drugs with potential therapeutic applications.
Used in the Development of Advanced Materials:
9H-Carbazole, 9-[1-(1-naphthalenylmethylene)-3-phenyl-2-propenyl]-, (Z,E)is also employed in the research and development of advanced materials, such as organic semiconductors, optoelectronic devices, and other high-tech applications. Its unique molecular structure and properties may contribute to the creation of new materials with improved performance and functionality.
Used in Pharmaceutical Development:
9H-Carbazole, 9-[1-(1-naphthalenylmethylene)-3-phenyl-2-propenyl]-, (Z,E)is used as a key component in the design and synthesis of new pharmaceuticals. Its potential biological activity and unique structural features make it a promising candidate for the development of novel drugs with specific therapeutic targets and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 190518-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,5,1 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 190518-89:
(8*1)+(7*9)+(6*0)+(5*5)+(4*1)+(3*8)+(2*8)+(1*9)=149
149 % 10 = 9
So 190518-89-9 is a valid CAS Registry Number.
190518-89-9Relevant academic research and scientific papers
Synthesis, structure and stability of E/Z-isomers of novel conjugated enamines prepared from 9-arylmethyl- or 9-arylpropenyl-9H-carbazole with arylmethyleneanilines
Paventi, Martino,Hay, Allan S.
, p. 1059 - 1068 (2007/10/03)
Active methylene groups, substituted by 9H-carbazol-9-yl (Carb) and aryl or 2-phenylethenyl groups, condense with arylmethyleneanilines in DMF at 75°C in the presence of Bu'OK to form the corresponding enamines [(Carb)(Ar1)C=C(Ar2)H] and dienamines [(Ar3)HC=C(Carb)CH=CHPh] in almost quantitative yield. The 1H and 13C NMR spectra for the enamine 1′Z-isomers [16 (Ar1 = Ar2 = 4-fluorophenyl), 17 (Ar1 = 4-fluorophenyl, Ar2 = 4-tert-butoxyphenyl), 19 (Ar1 = Ar2 = 4-tert-butoxyphenyl)], dienamine 1′Z-isomers [14a (Ar3 = 1-naphthyl), 14b (Ar3 = 4-methoxyphenyl), 14c (Ar3 = Ph)] and 1′E-isomers [15a (Ar3 = 1-naphthyl), 15c (Ar3 = Ph)] and precursors are assigned with the aid of COSY, HMBC, and HMQC techniques. The geometrical isomerism of the different dienamines 14-15 is established by 3JC-H NMR couplings and that of enamine 12 by a difference NOE experiment. X-Ray crystal structures for 16, 14a and 15c corroborate the isomerism results deduced by NMR studies. Dienamines 14a and 15a hydrolyse to the ketone under relatively strong acid conditions [AcOH-HCl-H2O (18:1:1 v/v)] under reflux over 7 h. There is an equilibrium between 14c and 15c in 1,2,4-trichlorobenzene at 180 ± 1°C with K = 15c/14c = 0.77 as estimated from the kinetic rate profiles from HPLC data acquired over 4 days. However, under the same conditions, 14a and 15a undergo an equilibration concurrent with a reaction (monitored over 9 days) giving apparently a carbazolyl-substituted phenylphenanthrene. In contrast, enamine 16 is thermally stable with no detectable change after boiling for 4 days in 1,2,4-trichlorobenzene.
