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19056-26-9

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19056-26-9 Usage

General Description

Quindecamine is a natural alkaloid compound found in the bark and leaves of the cinchona tree in South America. It is a member of the quinoline family and is structurally related to quinine, a well-known antimalarial drug. Quindecamine has been studied for its potential pharmacological properties, including antimalarial, antiparasitic, and anti-inflammatory effects. It has also shown promise as an antitumor agent, with some research indicating its ability to inhibit the growth of cancer cells. Quindecamine’s diverse biological activities make it an interesting target for further investigation and potential drug development. However, more research is needed to fully understand its mechanisms of action and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 19056-26-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,5 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19056-26:
(7*1)+(6*9)+(5*0)+(4*5)+(3*6)+(2*2)+(1*6)=109
109 % 10 = 9
So 19056-26-9 is a valid CAS Registry Number.
InChI:InChI=1/C30H38N4/c1-23-21-29(25-15-9-11-17-27(25)33-23)31-19-13-7-5-3-4-6-8-14-20-32-30-22-24(2)34-28-18-12-10-16-26(28)30/h9-12,15-18,21-22H,3-8,13-14,19-20H2,1-2H3,(H,31,33)(H,32,34)

19056-26-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N'-bis(2-methylquinolin-4-yl)decane-1,10-diamine

1.2 Other means of identification

Product number -
Other names Quindecamina

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19056-26-9 SDS

19056-26-9Downstream Products

19056-26-9Relevant articles and documents

Development of Single-Stranded DNA Bisintercalating Inhibitors of Primase DnaG as Antibiotics

Green, Keith D.,Punetha, Ankita,Chandrika, Nishad Thamban,Hou, Caixia,Garneau-Tsodikova, Sylvie,Tsodikov, Oleg V.

, p. 1986 - 1995 (2021)

Many essential enzymes in bacteria remain promising potential targets of antibacterial agents. In this study, we discovered that dequalinium, a topical antibacterial agent, is an inhibitor of Staphylococcus aureus primase DnaG (SaDnaG) with low-micromolar minimum inhibitory concentrations against several S. aureus strains, including methicillin-resistant bacteria. Mechanistic studies of dequalinium and a series of nine of its synthesized analogues revealed that these compounds are single-stranded DNA bisintercalators that penetrate a bacterium by compromising its membrane. The best compound of this series likely interacts with DnaG directly, inhibits both staphylococcal cell growth and biofilm formation, and displays no significant hemolytic activity or toxicity to mammalian cells. This compound is an excellent lead for further development of a novel anti-staphylococcal therapeutic.

P Toluenesulphonyl derivatives of N,N' bis (4 quinolino 4 quinaldino/ 4 quinazolino and 9 acridino) polymethylene diamines as hypoglycemic agents

Deshpande,Datta,Singh

, p. 746 - 749 (2007/10/05)

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