190579-34-1Relevant articles and documents
Studies on cardiac ingredients of plants. XIII: Chemical modification of gitoxin to cardiotonic compounds without vascular contractile effect
Nagatsu, Akito,Nakamura, Yukitaka,Takemoto, Kouya,Shibatomi, Kazutaka,Nagai, Shin-Ichi,Ueda, Taisei,Sakakibara, Jinsaku,Hidaka, Hiroyoshi,Fujita, Michiko,Hotta, Yoshihiro,Takeya, Kazumi,Asano, Masahisa,Hashimoto, Toshihiro,Asakawa, Yoshinori
, p. 599 - 607 (2007/10/03)
Nitrated gitoxins (4) and bufotoxin homologues with various lengths of alkyl chain at C-3 of the steroid nucleus (10) were prepared from gitoxin (1). The pharmacological activities of the resulting compounds (4 and 10) were evaluated by measurement of inh