190584-59-9

Upstream product

• 207398-91-2 [2,2-Dimethyl-prop-(E)-ylidene]-((S)-1-phenyl-ethyl)-amine 
• 190584-55-5 (3R,4S)-3-Benzyloxy-4-tert-butyl-1-((S)-1-phenyl-ethyl)-azetidin-2-one 

Downstream Products

• 190584-73-7 (R)-2-[(S)-3,3-Dimethyl-2-((S)-1-phenyl-ethylamino)-butyrylamino]-3-phenyl-propionic acid benzyl ester 
• 190584-66-8 (S)-2-[(S)-3,3-Dimethyl-2-((S)-1-phenyl-ethylamino)-butyrylamino]-3-methyl-butyric acid benzyl ester 
• 190584-63-5 (S)-4-tert-Butyl-3-((S)-1-phenyl-ethyl)-oxazolidine-2,5-dione 

Relevant academic research and scientific papers

Synthesis of (S)- and (R)-tert leucine enabling direct coupling with α-amino acid esters via β-lactam-derived α-amino acid N-carboxy anhydrides

(3S, 4R)- and (3R, 4S)-3-hydroxy-4-tert-butyl β-lactams on exposure to 1M NaOCl and a catalytic amount of 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) afforded α-amino acid N-carboxy anhydrides formally derived from both (S)- and (R)-tert-leucine amino acids.