190587-03-2Relevant academic research and scientific papers
Studies on selectin blockers. 6. Discovery of homologous fucose sugar unit necessary for E-selectin binding
Hiramatsu, Yasuyuki,Moriyama, Hideki,Kiyoi, Takao,Tsukida, Takahiro,Inoue, Yoshimasa,Kondo, Hirosato
, p. 2302 - 2307 (1998)
We describe a mimic of the sugar unit of the E-selectin ligand, sialyl Lewis X (sLe(X)). Carbohydrates are entering the realm of rational drug design, aided by the growing understanding of the structure-function relationships. We investigated a new method
