190598-41-5

Upstream product

• 108827-49-2 H-Pro-OTmse 
• 190598-38-0 (2S,3S)-3-tert-Butoxycarbonylamino-2-phenylselanyl-butyric acid 
• 34837-55-3 Phenylselenyl bromide 
• 106539-14-4 (S)-methyl 3-(tert-butyloxycarbonylamino)butyrate 

Downstream Products

• 190598-42-6 (S)-1-[(2S,3S)-3-((S)-2-tert-Butoxycarbonylamino-propionylamino)-2-phenylselanyl-butyryl]-pyrrolidine-2-carboxylic acid 2-trimethylsilanyl-ethyl ester 
• 190598-43-7 ((S)-1-{(1S,2S)-3-[(S)-2-((S)-1-Dimethylcarbamoyl-2-methyl-propylcarbamoyl)-pyrrolidin-1-yl]-1-methyl-3-oxo-2-phenylselanyl-propylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 190598-44-8 (S)-1-{(2S,3S)-2-Phenylselanyl-3-[(S)-2-(2,2,2-trifluoro-acetylamino)-propionylamino]-butyryl}-pyrrolidine-2-carboxylic acid ((S)-1-dimethylcarbamoyl-2-methyl-propyl)-amide 

Relevant academic research and scientific papers

Design of a novel secondary structure scaffolding device: Induction of a reverse turn in tetrapeptides by incorporating a β-amino acid and stereocontrolled free radical α-substitution reactions in peptide motifs

The incorporation of α-substituted β-amino acids into a tetrapeptide motif induces a reverse rum in aprotic solvent systems as revealed by NOESY and ROESY techniques, and by CD spectra. The conformations of these compounds have been studied by molecular modeling, and further supported by performing a highly stereoselective free radical allylation reaction on an α-phenylseleno β-amino acid unit within the tetrapeptide.