190604-92-3

Usage

Uses

Used in Pest Control Industry:
Acetamidiprid-n-desmethyl is used as an insecticide for its potent insecticidal and neuroblocking activities. It is particularly effective against a variety of pests, including aphids, whiteflies, and thrips, which are known to cause significant damage to crops. The compound works by targeting the nicotinic acetylcholine receptors in the central nervous system of insects, leading to paralysis and eventual death.
Additionally, acetamiprid-n-desmethyl is used as a neuroblocker in the study and understanding of the nervous system in animals. Its ability to target and modulate the activity of nicotinic acetylcholine receptors makes it a valuable tool in research related to neurophysiology and the development of new treatments for neurological disorders.

Upstream product

• 5652-84-6 methyl N-cyanoacetimidate 
• 97004-04-1 5-(aminomethyl)-2-chloropyridine 
• 135410-20-7 acetamiprid 

Relevant academic research and scientific papers

Reaction kinetics and mechanisms of neonicotinoid pesticides with sulfate radicals

The reaction kinetics and mechanisms of three neonicotinoid insecticides, imidacloprid (IMD), thiacloprid (THIA) and acetamiprid (ACT) with sulfate radicals were studied by flash-photolysis of peroxodisulfate, S 2O82-. The absolute rate constants (3 ± 1) × 108, (1.1 ± 0.6) × 109, and (3 ± 1) × 109 M-1 s-1 were determined for IMD, ACT, and THIA, respectively. The reactivity and absorption spectra of the observed organic intermediates are in line with those reported for α-aminoalkyl radicals, and their absorption spectra agree very well with those estimated employing the time-dependent density functional theory with explicit account for bulk solvent effects. The mono- and di-hydroxylated oxidation products of the insecticides were identified as primary degradation products. The proposed reaction mechanism supports an initial charge transfer from the amidine nitrogen of the insecticides to the sulfate radicals. The pyridine moiety of the insecticides remains unaffected even after long irradiation times, until nicotinic acid is formed.

N'-Cyano-N-Halogenalkylimidamide Derivatives

The present application relates to novel substituted N′-cyano-N-halogenalkylimidamide derivatives, to processes for their preparation and to their use for controlling animal pests, especially arthropods, in particular insects.