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19064-18-7

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19064-18-7 Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

2,6-Difluorobenzyl alcohol is used to get 2-(bromomethyl)-1,3-difluorobenzene.

Check Digit Verification of cas no

The CAS Registry Mumber 19064-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,6 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19064-18:
(7*1)+(6*9)+(5*0)+(4*6)+(3*4)+(2*1)+(1*8)=107
107 % 10 = 7
So 19064-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H11BrO3/c6-1-5(2-7,3-8)4-9/h7-9H,1-4H2

19064-18-7 Well-known Company Product Price

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  • Alfa Aesar

  • (A18336)  2,6-Difluorobenzyl alcohol, 97%   

  • 19064-18-7

  • 5g

  • 439.0CNY

  • Detail
  • Alfa Aesar

  • (A18336)  2,6-Difluorobenzyl alcohol, 97%   

  • 19064-18-7

  • 25g

  • 1491.0CNY

  • Detail

19064-18-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,6-difluorophenyl)methanol

1.2 Other means of identification

Product number -
Other names (2,6-Difluorophenyl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19064-18-7 SDS

19064-18-7Relevant articles and documents

Preparation method of 2, 6-difluorobenzyl alcohol

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Paragraph 0027-0069, (2021/11/10)

The invention discloses a preparation method of 2, 6-difluorobenzyl alcohol. By adding a phase transfer catalyst, a reduction reaction can be carried out in two phases, and the yield of the reduction reaction can be obviously improved. Part of NaBH4 is dissolved in advance, and the rest NaBH4 is added in batches subsequently, so that the reduction efficiency of the NaBH4 is improved, and the purpose of improving the yield of the reduction reaction is finally achieved. By adding a Lewis acid catalyst, the reduction reaction yield can be effectively improved, the purity of 2, 6-difluorobenzyl alcohol is improved, and the residual amount of methyl 2, 6-difluorobenzoate is reduced.

Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency

Bollini, Mariela,Gallardo-Macias, Ricardo,Spasov, Krasimir A.,Tirado-Rives, Julian,Anderson, Karen S.,Jorgensen, William L.

, p. 1110 - 1113 (2013/03/14)

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved activity towards Tyr181Cys containing variants was pursued with the assistance of free energy perturbation (FEP) calculations. Optimization of the 4-R substituent in 1 led to ethyl and isopropyl analogs 1e and 1f with 1-7 nM potency towards both the wild-type virus and a Tyr181C variant.

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