190661-97-3Relevant academic research and scientific papers
Preparation of diastereomerically pure dilignol model compounds
Buendia, Julien,Mottweiler, Jakob,Bolm, Carsten
, p. 13877 - 13882 (2011)
A gram-scale synthetic access to diastereomerically pure dilignol β-O-4 type model compounds, which represent valuable candidates for studies of lignin cleavage and valorization, is described. Following a straightforward procedure both diastereoisomers of 1,3-dilignols can be prepared. In the key-step, tert-butyl aryloxy esters are used as enolate precursors for additions on aldehydes. After separation, the resulting erythro and threo β-hydroxy esters are independently reduced to afford the target compounds in high yields.
