190668-54-3Relevant academic research and scientific papers
Enantioselective Synthesis of 2,2-Dialkyl-3-butenals by Alkylation of (4S,5S)-ADPD-imines
Mino, Takashi,Saitoh, Munenobu,Yamashita, Masakazu
, p. 3981 - 3983 (1997)
(S)-2-Alkyl-2-methyl-3-butenals that have a quaternary stereogenic carbon atom at the α-position were obtained from 2-methyl-2-butenal (4S,5S)-ADPD-imine in good enantioselective excesses (up to 81% ee). Using this reaction, a novel sesquiterpene, (+)-(E)-2,5,9-trimethyl-2-vinyl-4,8-decadienal, was synthesized with moderate enantioselectivity (53% ee).
