190671-78-4Relevant academic research and scientific papers
Synthesis of chiral phosphetanes
Marinetti, Angela,Kruger, Virginie,Buzin, Francois-Xavier
, p. 2947 - 2950 (1997)
Reactions of lithium phosphides with the mesylate, or the cyclic sulfate, of (R,R)-2,4-pentanediol afford a general access to new chiral ligands based on the phosphetane moiety. Amongst others, the four membered ring analogue of Me-DuPHOS has been obtained by this method.
Chiral 1,2-bis(phosphetano)benzenes: Preparation and use in the Ru- catalyzed hydrogenations of carbonyl derivatives
Marinetti, Angela,Genet, Jean-Pierre,Jus, Sebastien,Blanc, Delphine,Ratovelomanana-Vidal, Virginie
, p. 1160 - 1165 (2007/10/03)
Chiral 1,2-bis(phosphetano)benzenes are readily prepared from accessible, optically pure 1,3-diol cyclic sulfates. Their ruthenium complexes catalyze the enantioselective hydrogenations of functionalized carbonyls with moderate-to-high enantiomeric excesses. High levels of diastereo- and enantioselectivity are achieved, especially in the hydrogenation of β-diketones to the corresponding anti-1,3-diols.
