190723-59-2Relevant articles and documents
2′,3′-Cyclopropanated Nucleoside Dimers
Yannopoulos, Constantin G.,Zhou, Wen-Qiang,Nower, Peter,Peoc'h, Didier,Sanghvi, Yogesh S.,Just, George
, p. 378 - 380 (2007/10/03)
Syntheses of three novel conformationally rigid dimers containing cyclopropyl -amide and -sulfonamide functionalities are described. Their incorporation into an oligonucleotide sequence resulted in considerable lowering of the Tm's in binding to their complementary RNA sequences.