190725-06-5

Upstream product

• 190725-03-2 tert-Butyl-dimethyl-((S)-5-phenylsulfanyl-2,5-dihydro-furan-2-ylmethoxy)-silane 
• 183075-05-0 (2R,3S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-5-phenylsulfanyl-tetrahydro-furan-3-ol 
• 183075-04-9 phenyl 2-deoxy-1-thio-D-erythro-pentofuranoside 
• 452-51-7 D-2-deoxyribose 
• 108-98-5 thiophenol 

Relevant academic research and scientific papers

Facile synthesis of 2',3'-unsaturated nucleosides from 2-deoxyribose

A straightforward approach for the synthesis of 2',3'-unsaturated nucleosides starting from 2-deoxyribose is described. This novel route involves two new methods; (1) preparation of 2-deoxy-1-thioribofuranoside by direct condensation of 2-deoxyribose and thiophenol, (2) formation of the nucleoside skeleton by the direct coupling of 2,3-unsaturated 1-thiopentofuranoside with pyrimidine bases.