19075-53-7Relevant articles and documents
PPAR (peroxisome proliferator-activated receptor) agonist and application thereof to treatment of senile dementia and other diseases
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, (2018/07/30)
The invention relates to a compound, namely a gamma-subtype peroxisome proliferator-activated receptor (PPAR) agonist. In addition, the invention discloses a medicinal component and a preparation containing the compound and application of such the gamma-subtype PPAR agonist.
Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors
De Vreese, Rob,Van Steen, Nicholas,Verhaeghe, Tom,Desmet, Tom,Bougarne, Nadia,De Bosscher, Karolien,Benoy, Veronick,Haeck, Wanda,Van Den Bosch, Ludo,D'Hooghe, Matthias
supporting information, p. 9868 - 9871 (2015/06/16)
A small library of 3-[(4-hydroxycarbamoylphenyl)aminomethyl]benzothiophenes was prepared and assessed as a novel class of HDAC6 inhibitors, leading to the identification of three representatives as potent and selective HDAC6 inhibitors. Further tests with
Pharmaceutical compounds
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, (2008/06/13)
This invention relates to compounds of formula (I) where R1 to R12, —W—V—, —X—Y—, m and n have the values defined in claim 1, their preparation and use as pharmaceuticals.