190774-15-3

Upstream product

• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 10272-07-8 3.5-dimethoxyaniline 
• 190774-12-0 5,7-dimethoxy-3-(4-methoxyphenyl)-1,2-dihydro-2-quinolinone 
• 68-12-2 N,N-dimethyl-formamide 
• 190774-14-2 N-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acetamide 

Relevant academic research and scientific papers

Synthesis of 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2- or 4-ones and derivatives

Condensation of ethyl 2-(4-methoxyphenyl)-3-hydroxyacrylate with 3,5-dimethoxyaniline afforded, depending on experimental conditions, either 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2-one or 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-4-one. Whereas chlorination with phosphorous oxychloride led to the corresponding 2- and 4- chloroquinolines derivatives, 2-chloro-3-(4-methoxyphenyl)-5,7-dimethoxyquinoline was also obtained by using the Meth Cohn method's.