190789-37-8Relevant academic research and scientific papers
Stereoselective alkylation of sulfoxides and sulfones derived from (R)-cysteine
Dehmlow, Eckehard Volker,Pieper, Stefanie,Neumann, Beate,Stammler, Hans-Georg
, p. 1013 - 1018 (1997)
(R)-Cysteinol was protected as its oxazoline derivatives 1a-c and oxidized to the sulfoxides 2, 3 and the sulfone 7. These compounds could be alkylated under chelate control to give tertiary and quaternary stereogenic centers in a highly stereoselective manner to yield 4a-c,5, 8a-c, 11 and 12. Starting with the sulfone 7, both configurations at the new chiral center can be constructed. VCH Verlagsgesellschaft mbH, 1997.
