190840-29-0

Basic information

• Product Name: N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester
• Synonyms: (2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester;N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester
• CAS NO: 190840-29-0
• Molecular Formula: C₈H₁₅N₇O₂
• Molecular Weight: 241.2504
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 190840-29-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester(190840-29-0)
• EPA Substance Registry System: N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester(190840-29-0)

Safety Data

• Hazardous Substances Data: 190840-29-0(Hazardous Substances Data)

Usage

Uses

(2,3-Diazidopropyl)-carbamic Acid 1,1-Dimethylethyl Ester can be used in the preparation of Vestipitant and in the preparation of tricyclic erythromycins.

Upstream product

• 137618-48-5 tert-butyl N-(2,3-dihydroxypropyl)carbamate 

Downstream Products

• 1208864-72-5 C₁₇H₁₉F₆N₇O₂ 
• 163133-92-4 1,2-diamino-3-(BOC-amino)propane 

Relevant articles and documents

Convenient and simplified approaches to w-monoprotected triaminopropane derivatives: Key intermediates for bifunctional chelating agent synthesis

High yields of selectively Ar-protected-1,2,3-triaminopropanes (1,3 or 1,2 functionalized diamines) were obtained in 6 or 4 steps from diamino alcohols or aminodiols, respectively. These two multi-step procedures involve protection of the amino group, substitution of the hydroxy group by an azido group and selective reduction. The conditions for the first procedure allow the preparation of various Af2-monoprotected-l,2,3-triaminopropanes 6a, 6b, but the second one is more convenient for obtaining N1-Boc-1,2,3-triaminopropane 6'. These two simplified procedures, which provide functionalized 1,2 or 1,3 diamines easily and with good overall yields, could be useful for the synthesis of : bifunctional chelating agents.