190840-29-0 Usage
Uses
Used in Pharmaceutical Industry:
N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester is used as a synthetic intermediate for the preparation of Vestipitant, a drug that acts as a neurokinin-3 receptor antagonist. It is utilized in the treatment of various conditions, such as depression and anxiety, by targeting specific receptors in the brain.
Additionally, N-(2,3-Diazidopropyl)-carbaMic Acid 1,1-DiMethylethyl Ester is used as a synthetic intermediate for the preparation of tricyclic erythromycins, which are a class of macrolide antibiotics. These antibiotics are effective against a wide range of bacterial infections, including respiratory, skin, and soft tissue infections, due to their ability to inhibit bacterial protein synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 190840-29-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,8,4 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 190840-29:
(8*1)+(7*9)+(6*0)+(5*8)+(4*4)+(3*0)+(2*2)+(1*9)=140
140 % 10 = 0
So 190840-29-0 is a valid CAS Registry Number.
190840-29-0Relevant academic research and scientific papers
Convenient and simplified approaches to w-monoprotected triaminopropane derivatives: Key intermediates for bifunctional chelating agent synthesis
Benoist, Eric,Loussouarn, Anthony,Remaud, Patricia,Chatal, Jean-Francois,Gestin, Jean-Francois
, p. 1113 - 1118 (2007/10/03)
High yields of selectively Ar-protected-1,2,3-triaminopropanes (1,3 or 1,2 functionalized diamines) were obtained in 6 or 4 steps from diamino alcohols or aminodiols, respectively. These two multi-step procedures involve protection of the amino group, substitution of the hydroxy group by an azido group and selective reduction. The conditions for the first procedure allow the preparation of various Af2-monoprotected-l,2,3-triaminopropanes 6a, 6b, but the second one is more convenient for obtaining N1-Boc-1,2,3-triaminopropane 6'. These two simplified procedures, which provide functionalized 1,2 or 1,3 diamines easily and with good overall yields, could be useful for the synthesis of : bifunctional chelating agents.
