190850-76-1Relevant articles and documents
Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors.
Kim,Bae,So,Yoo,Chang,Lee,Kang
, p. 2349 - 2351 (2007/10/03)
[reaction: see text] Chiral aziridine derivative 1 was prepared from D-tartaric acid. This compound could be utilized as a common intermediate for the synthesis of hydroxyethylamine class HIV protease inhibitors such as saquinavir, amprenavir, or nelfinavir.
Catalytic asymmetric synthesis of new halogenated chiral synthons
Vanhessche, Koen P. M.,Sharpless, K. Barry
, p. 517 - 522 (2007/10/03)
Two-step and practical asymmetric syntheses of enantiomerically pure 4-trifluoromethyl-2.2-dioxo-1,3,2-dioxathiolane and 4-trichloromethyl-2,2-dioxo-1,3,2-dioxathiolane (>98% ee) have been achieved. Catalytic asymmetric dihydroxylation (AD) of 3,3,3-trifl