190851-19-5

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 97-52-9 2-methoxy-4-nitrophenylamine 
• 911365-00-9 2-methoxy-4-nitrophenylcarbamic acid tert-butyl ester 

Downstream Products

• 1027334-95-7 C₂₇H₃₁N₃O₅ 
• 1332220-13-9 4-tert-butyl-N-[[4-[(2-chlorobenzene-carboximidoyl)amino]-3-methoxy-phenyl]carbamothioyl]benzamide 
• 1332220-07-1 4-tert-butyl-N-[[4-[(2-chlorophenyl)-methylamino]-3-methoxy-phenyl]-carbamothioyl]-benzamide 
• 1332451-08-7 N-[(4-amino-3-methoxy-phenyl)carbamothioyl]-4-tert-butyl-benzamide 
• 1332220-32-2 tert-butyl N-[4-[(4-tert-butylbenzoyl)carbamothioylamino]-2-methoxy-phenyl] carbamate 

Relevant academic research and scientific papers

AMIDO-SUBSTITUTED AZOLE COMPOUNDS

The present invention relates to amido-substituted azole compounds of general formula (I), in which X1, X2, R1, R2, R4, R5, R7 and R8 are as defined in the claims which are inhibitors of TNKS1 and/or TNKS2, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.

Glutamate receptor photomodulators

The present invention relates to the discovery of particular aromatic compounds of formula (1), possessing activity as modulators of metabotropic glutamate receptors (mGIuR) whose modulatory activity on the receptor may be controlled by irradiation with suitable light resulting in the optical control of receptor biological function, to the use of said compounds as a medicament, and to pharmaceutical compositions comprising said compounds of formula (1).

Two-photon fluorescent probes for acidic vesicles in live cells and tissue

(Figure Presented) Move with the groove: Two-photon fluorescent pH probes and a two-photon lysotracker (AL1) can visualize acidic vesicles in live cells and living tissue for a long period of time without mistargeting and photobleaching problems. Using AL1, vesicles can be tracked in real time (see picture).