190852-60-9Relevant academic research and scientific papers
A chiral (alkoxy)methyl-substituted silicon group as an auxiliary for the stereoselective cuprate addition to α,β-unsaturated ketones: Synthesis of (-)-(R)-phenyl 2-phenylpropyl ketone
Bratovanov, Svetoslav,Bienz, Stefan
, p. 1587 - 1603 (2007/10/03)
The [(benzyloxy)methyl](tert-butyl)methylsilyl group was used as the chiral auxiliary to effect highly diastereoselective conjugate additions of organocuprates to enones. Thus, reaction of several R2CuLi with α-silylated α,β-unsaturated ketones
