19094-55-4

Basic information

• Product Name: 3,5-diiodo-2-methoxybenzoic acid
• CAS NO: 19094-55-4
• Molecular Formula: C₈H₆I₂O₃
• Molecular Weight: 403.9404
• Mol File: 19094-55-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 441.4°C at 760 mmHg
• Flash Point: 220.7°C
• Density: 2.374g/cm³
• Vapor Pressure: 1.44E-08mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 3,5-diiodo-2-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diiodo-2-methoxybenzoic acid(19094-55-4)
• EPA Substance Registry System: 3,5-diiodo-2-methoxybenzoic acid(19094-55-4)

Safety Data

• Hazardous Substances Data: 19094-55-4(Hazardous Substances Data)

Upstream product

• 133-91-5 3,5-diiodosalicylic acid 
• 74-88-4 methyl iodide 
• 121789-21-7 methyl 3,5-diiodo-2-methoxybenzoate 

Downstream Products

• 1613336-62-1 3,5-diiodo-2-methoxy-N-methyl-N-(4-phenoxyphenyl)benzamide 
• 1613336-60-9 3,5-diiodo-2-methoxy-N-(4-phenoxyphenyl)benzamide 
• 1613336-66-5 N-(4-(4-chlorophenoxy)phenyl)-3,5-diiodo-2-methoxybenzamide 
• 1613336-71-2 3,5-diiodo-2-methoxy-N-(naphthalen-2-yl)benzamide 
• 101495-51-6 3,5-Diiod-2-methoxybenzoylchlorid 
• 121789-50-2 2-(3,5-Diiod-2-methoxybenzoyl)-4-4-diethoxy-2-ethoxycarbonylbutansaeure-ethylester 
• 121789-49-9 3-(3,5-Diiod-2-methoxyphenyl)-2-(1-hydroxyethyliden)-3-oxopropionsaeure-ethylester 
• 121789-48-8 2-Acetyl-3-(3,5-diiod-2-methoxyphenyl)-3-hydroxy-2-acrylsaeureethylester 
• 121789-51-3 3,5-Diiod-2-methoxybenzoesaeure-ethylester 

Relevant articles and documents

INHIBITORS OF PROTEIN ARGININE DEIMINASE 1 AND METHODS OF PREPARATION AND USE THEREOF

The invention provides novel inhibitors or inactivators of protein arginine deiminase 1, pharmaceutical compositions and methods of use thereof. The invention also relates to molecular probes based on such compounds and methods of use thereof.

Dual protonophore-chitinase inhibitors dramatically affect O. Volvulus molting

The L3-stage-specific chitinase OvCHT1 has been implicated in the development of Onchocerca volvulus, the causative agent of onchocerciasis. Closantel, a known anthelmintic drug, was previously discovered as a potent and specific OvCHT1 inhibitor. As closantel is also a known protonophore, we performed a simple scaffold modulation to map out the structural features that are relevant for its individual or dual biochemical roles. Furthermore, we present that either OvCHT1 inhibition or protonophoric activity was capable of affecting O. volvulus L3 molting and that the presence of both activities in a single molecule yielded more potent inhibition of the nematode's developmental process.