190957-88-1 Usage
General Description
Ethyl furo[3,2-c]pyridine-4-carboxylate is a chemical compound with the molecular formula C12H9NO3. It is a nitrogen-containing heterocyclic compound, consisting of a furo[3,2-c]pyridine ring system with an ethyl ester group attached to the carboxylic acid moiety. Ethyl furo[3,2-c]pyridine-4-carboxylate is often used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It possesses a unique structure that may impart specific biological activity or pharmacological properties. The synthesis and structural modification of ethyl furo[3,2-c]pyridine-4-carboxylate derivatives are of interest in medicinal chemistry for designing new drugs with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 190957-88-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,9,5 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 190957-88:
(8*1)+(7*9)+(6*0)+(5*9)+(4*5)+(3*7)+(2*8)+(1*8)=181
181 % 10 = 1
So 190957-88-1 is a valid CAS Registry Number.
190957-88-1Relevant articles and documents
Furopyridines. XXI [1]. Synthesis of Cyano Derivatives of Furo-[2,3-b]-,-[2,3-c]- And -[3,2-c]pyridine and Their Conversion to Derivatives Having Another Carbon-substituent
Shiotani, Shunsaku,Taniguchi, Katsunori
, p. 493 - 499 (2007/10/03)
Cyanation of furo[2,3-b]-, -[2,3-c]- and -[3,2-c]pyridine N-oxides 1a, 1b and 1c by the Reissert-Henze method, reaction with benzoyl chloride and trimethylsilyl cyanide in dichloromethane and the reaction with trimethylsilyl cyanide and triethylamine in acetonitrile afforded 6-cyanofuro[2,3-b]- 2a, 7-cyanofuro[2,3-c]- 2b and 4-cyanofuro[3,2-c]pyridine 2c in moderate to excellent yield. The cyano group in 2a, 2b and 2c was converted to carboxamides 3a, 3b and 3c, ethyl imidates 5a, 5b and 5c and ethyl carboxylates 6a, 6b and 6c. Reaction of the N-oxides with trimethylsily bromide in acetonitrile gave the deoxygenated furopyridine 7a and 7d, bifuropyridyl 8b and 8c, and the N-oxide 9 of 8c.
