190964-91-1

Basic information

• Product Name: tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate
• Synonyms: 1-Piperidinecarboxylic acid, 4-(4-Methyl-1-piperazinyl)-, 1,1-diMethylethyl ester;tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate;4-(4-Methyl-1-piperazinyl)-1-piperidinecarboxylic acid tert-butyl ester
• CAS NO: 190964-91-1
• Molecular Formula: C15H29N3O2
• Molecular Weight: 283.41
• Mol File: 190964-91-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 370.2 °C at 760 mmHg
• Flash Point: 177.7 °C
• Appearance: /
• Density: 1.061
• CAS DataBase Reference: tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate(190964-91-1)
• EPA Substance Registry System: tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate(190964-91-1)

Safety Data

• Hazardous Substances Data: 190964-91-1(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate is a chemical compound that consists of a piperidine ring with a tert-butyl and a methylpiperazine group attached to it. It is commonly used as a precursor in the synthesis of pharmaceutical drugs and other organic compounds. The tert-butyl group provides steric hindrance, making the molecule more rigid and less prone to degradation. The presence of the piperazine ring in the molecule contributes to its biological activity, as piperazine derivatives have been found to possess a wide range of pharmacological properties. tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate may also have use in research and development as a building block for the creation of new chemical entities with potential therapeutic applications.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1219979-73-3 1-methyl-4-(piperidin-4-yl)piperazine monohydrochloride 

Relevant articles and documents

ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR

Disclosed is a class of new aryl-phosphorus-oxygen compounds as shown in formula (I) as EGFR kinase inhibitors, and pharmaceutically acceptable salts thereof.

CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The cyclic amine derivative is represented by formula, a prodrug thereof or a pharmacologically acceptable salt thereof: wherein A represents a group represented by Formula (IIa), (IIb) or (IIc): wherein R3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R4 represents a hydrogen atom or an alkylcarbonyl group having 2 to 6 carbon atoms or an alkyl group having 1 to 6 carbon atoms and optionally substituted with an alkylcarbonylamino group having 2 to 6 carbon atoms and n represents 1 or 2, in which when R3 and R4 each independently represent an alkyl group having 1 to 6 carbon atoms, R1 represents an alkyl group having 1 to 6 carbon atoms and substituted with a hydroxyl group, an amino group or a carboxyl group.

5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF

Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.