190964-91-1

Usage

Uses

Used in Pharmaceutical Synthesis:
Tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate is used as a precursor in the synthesis of pharmaceutical drugs, leveraging its structural features to contribute to the development of new medications.
Used in Organic Chemistry:
In the field of organic chemistry, tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate is used as a building block for the creation of new chemical entities, potentially leading to the discovery of novel compounds with therapeutic applications.
Used in Research and Development:
Tert-butyl 4-(4-methylpiperazin-1-yl)piperidine-1-carboxylate is employed in research settings to explore its potential as a component in the design of new molecules with biological activity, particularly in the context of drug discovery and development.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 1219979-73-3 1-methyl-4-(piperidin-4-yl)piperazine monohydrochloride 

Relevant academic research and scientific papers

ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR

Disclosed is a class of new aryl-phosphorus-oxygen compounds as shown in formula (I) as EGFR kinase inhibitors, and pharmaceutically acceptable salts thereof.

A Anaplastic lymphoma kinase inhibitors (by machine translation)

The present invention of formula (I) compounds, of formula (I) compounds of the type (II) in the middle of the compound, of formula (III) compound and its preparation method. Formula (I) compound is a small molecule Anaplastic lymphoma kinase (Anaplastic

CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The cyclic amine derivative is represented by formula, a prodrug thereof or a pharmacologically acceptable salt thereof: wherein A represents a group represented by Formula (IIa), (IIb) or (IIc): wherein R3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R4 represents a hydrogen atom or an alkylcarbonyl group having 2 to 6 carbon atoms or an alkyl group having 1 to 6 carbon atoms and optionally substituted with an alkylcarbonylamino group having 2 to 6 carbon atoms and n represents 1 or 2, in which when R3 and R4 each independently represent an alkyl group having 1 to 6 carbon atoms, R1 represents an alkyl group having 1 to 6 carbon atoms and substituted with a hydroxyl group, an amino group or a carboxyl group.

SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR

Disclosed are a 2-aminopyridine derivative having protein kinase inhibition activity, a preparation method and a pharmaceutical composition thereof Also disclosed are uses of the compounds and the pharmaceutical compositions thereof in the preparation of drugs for treating and/or preventing protein kinase-related diseases.

5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF

Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.

1- (1,2-disubstituted piperidinyl) -4-substituted piperazine derivatives

This invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, as substance-P antagonists; their preparation, compositions containing them and their use as a medicin