190967-68-1 Usage
Description
R-Sulindac Sulfoxide is the R-epimer metabolite of Sulindac (S699215), a nonsteroidal anti-inflammatory drug (NSAID) with potential anti-cancer properties. It is derived from the metabolism of Sulindac and plays a role in the activation of the P450 system, which is involved in the oxidation of R-Sulindac.
Uses
Used in Pharmaceutical Industry:
R-Sulindac Sulfoxide is used as an intermediate in the synthesis of NSAIDs for its potential anti-inflammatory and analgesic properties. It contributes to the overall efficacy of the drug by participating in the activation of the P450 system, which is essential for the metabolism and oxidation of R-Sulindac.
Used in Anticancer Applications:
R-Sulindac Sulfoxide is used as a potential anti-cancer agent, particularly in the development of drugs targeting various types of cancer. Its role in the activation of the P450 system may contribute to the enhancement of the drug's therapeutic effects and the modulation of oncological signaling pathways, leading to the inhibition of tumor growth and progression.
Used in Drug Metabolism Research:
R-Sulindac Sulfoxide is used as a research compound in the study of drug metabolism, specifically in understanding the role of the P450 system in the oxidation of NSAIDs and other related compounds. This knowledge can be applied to improve the design and development of more effective and safer drugs for various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 190967-68-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,9,6 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 190967-68:
(8*1)+(7*9)+(6*0)+(5*9)+(4*6)+(3*7)+(2*6)+(1*8)=181
181 % 10 = 1
So 190967-68-1 is a valid CAS Registry Number.