19100-95-9Relevant academic research and scientific papers
A silver-initiated free-radical intermolecular hydrophosphinylation of unactivated alkenes
Li, Zejiang,Fan, Fenghua,Zhang, Zengyan,Xiao, Yingxia,Liu, Dong,Liu, Zhong-Quan
, p. 27853 - 27856 (2015/03/31)
A scalable, operationally easy intermolecular hydrophosphinylation of various unactivated alkenes with H-P(O) compounds via an Ag(i)-initiated free radical process was developed. Mechanistic studies including electron-spin-resonance (ESR) and radical clock experiments suggest that atom transfer processes were involved in this system.
Photoinduced hydrophosphinylation of alkenes with diphenylphosphine oxide
Kawaguchi, Shin-ichi,Nomoto, Akihiro,Sonoda, Motohiro,Ogawa, Akiya
scheme or table, p. 624 - 626 (2011/02/28)
Photoinduced hydrophosphinylation of alkenes with diphenylphosphine oxide took place regioselectively affording the corresponding phosphine oxide in good yields. This hydrophosphinylation is of simple operation and widely tolerant to a variety of the functionalities.
Air-induced anti-Markovnikov addition of secondary phosphine oxides and H-phosphinates to alkenes
Hirai, Takayoshi,Han, Li-Biao
, p. 53 - 55 (2007/10/03)
(Chemical Equation Presented) Air (oxygen) induces the addition of secondary phosphine oxides and H-phosphinates to alkenes to selectively produce the corresponding anti-Markovnikov adducts in good to high yields. Mechanistic studies show that the addition probably proceeds via a radical chain mechanism.
Stereochemically controlled Synthesis of Unsaturated Alcohols by the Horner-Wittig Reaction
Ayrey, Peter M.,Bolton, Michael A.,Buss, Antony D.,Greeves, Nicholas,Levin, Daniel,et al.
, p. 3407 - 3418 (2007/10/02)
Single isomers (E or Z) of unsaturated alcohols with two to five carbon atoms between the double bond and the OH group may be made by the phosphine oxide version of the Horner-Wittig reaction.Hydroxyalkyldiphenylphosphine oxides react with aldehydes either directly or as silyl ethers to give a moderately Z-selective synthesis, while rearrangement of esters of the same alcohols by acyl transfer or acylation of alkyldiphenylphosphine oxides with lactones gives hydroxy ketones whose reduction and elimination leads to an E-selective synthesis.In most cases, separation of the diastereoisomers of the Horner-Wittig intermediates leads to the preparation of pure E- or Z-alkenols.
SYNTHESIS OF SINGLE ISOMERS (E OR Z) OF UNSATURATED ALCOHOLS BY THE HORNER-WITTIG REACTION
Buss, Antony D,Greeves, Nicholas,Levin, Daniel,Wallace, Paul,Warren, Stuart
, p. 357 - 360 (2007/10/02)
Single isomers (E or Z) of homoallylic and higher alcohols can be synthesised from ω-hydroxyalkyldiphenylphosphine oxides and aldehydes, or from alkyldiphenylphosphine oxides and lactones
