191152-67-7Relevant academic research and scientific papers
Short and efficient synthesis of new α-oximino esters
Boukhris, Said,Souizi, Abdelaziz,Robert, Albert
, p. 4693 - 4696 (1996)
α-Cyano α-alkoxy carbonyl epoxides 1 react, in refluxing alcohol, with hydroxylamine hydrochloride 2 in a direct ring opening reaction to give β-alkoxy α-oximino esters 4 in good yields. We have shown that this reaction proceeds through the formation of c
A new method of synthesis of 2-alkoxycarbonyl3-aryl-3,4-dihydro quinoxalines and 2-alkoxycarbonyl-3-aryl quinoxalines
Abderrazak, Gaz,Abdelaziz, Souizi,Gerard, Coudert
, p. 3459 - 3465 (2007/10/03)
Cyanoesters epoxides 1, when treated with o-phenylenediamine in presence or absence of hydrogen chloride, at reflux of acetonitrile, give the 2- alkoxycarbonyl-3-aryl-3,4-dihydro quinoxalines and 2-alkoxy carbonyl-3-aryl quinoxalines in good yields.
Synthesis of β-chloro-α-cyano-α-hydroxyesters
Ouladyakhlef, Abdesalam,Boukhris, Said,Souizi, Abdelaziz,Robert, Albert
, p. 111 - 114 (2007/10/03)
Regioselective ring opening of 3-aryl-2-cyano 2-(methoxy and ethoxycarbonyl) oxiranes 1 with chlorhydric acids gave halohydrins 3 with OH, CN and CO2Me or CO2Et on the same carbon atom. - Keywords: oxirane; β-chloro-α-cyano-α-hydroxyester; ketoester; regi
Regioselective ring opening of 3-aryl-2-cyano-2-(methoxycarbonyl)oxiranes with metal halides and silica-gel-supported metal halides. Synthesis of substituted but-3-en-4-olides.
Brine, N.,Foucaud, A.
, p. 620 - 624 (2007/10/02)
Regioselective ring opening of 3-aryl-2-cyano-2-(methoxycarbonyl)oxiranes 1 with transition metal halides (copper(II) chloride, copper (II) bromide, zinc bromide, cobalt chloride and ferric chloride) and silica-gel-supported metal halides gave methyl 3-aryl-2-cyano-3-halo-2-hydroxypropanoates 5, 6 and methyl 3-aryl-3-halo-2-oxopropanoates 2, 3.The reaction of 1 in chlorobenzene under reflux with silica-gel-supported copper (II) halides gave but-3-en-4-olides 4.Key Words: methyl 3-aryl-2-cyano-3-halo-2-hydroxypropanoates; methyl 3-aryl-3-halo-2-oxopropanoates; but-3-en-4-olides.
