191155-23-4

Upstream product

• 34897-85-3 o-azidobenzoyl chloride 
• 191155-22-3 (3R,5aS,10bS,11aS)-10b-Allyl-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione 
• 96238-68-5 tert-butyl (+)-(S)-3-[2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl]-1H-indole-1-carboxylate 
• 191155-24-5 3a-allyl-2-fluorocarbonyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester 
• 191155-96-1 (2S,3aS,8aR)-3a-Allyl-2-((R)-1-methoxycarbonyl-ethylcarbamoyl)-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester 
• 4299-70-1 L-tryptophan methyl ester 

Relevant academic research and scientific papers

Total synthesis of 5-N-acetylardeemin and amauromine: Practical routes to potential MDR reversal agents

The total synthesis of the title compounds has been accomplished. The key step involves the kinetic stereoselective conversion of 19 → 20. The synthesis of 20 represents for the first time a direct method for constructing exo-pyrroloindoles from protected