191158-01-7Relevant academic research and scientific papers
Synthesis of a radiolabelled retinoid X receptor (RXR) specific ligand
Held, Pierre,Heck, Marie-Pierre,Iyer, Jaya,Gronemeyer, Hinrich,Lebeau, Luc,Mioskowski, Charles
, p. 501 - 507 (2007/10/03)
Synthesis of 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[1,3-dioxolan-2 -yl]-benzoic acid or SR11237, a specific ligand of Retinoid X Receptors, is described in a 3H-labelled version. The labelled retinoid was prepared in 5 steps and tritium was introduced through a final reduction of an aromatic dihalide moiety with 3H2.
