19116-90-6

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,5-Dimethoxybenzenesulfonamide is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and improved products in these fields.
Used in Dye and Pigment Production:
2,5-DIMETHOXYBENZENESULFONAMIDE is utilized as an intermediate for the production of dyes and pigments, enhancing the color properties and performance of these materials in various applications.
Used as a Catalyst in Chemical Reactions:
2,5-Dimethoxybenzenesulfonamide serves as a catalyst in a range of chemical reactions, facilitating and accelerating these processes to improve efficiency and yield.
Used in Pharmaceutical Preparation:
As a reagent, 2,5-Dimethoxybenzenesulfonamide is employed in the preparation of various pharmaceuticals, playing a crucial role in the synthesis and formulation of these medications.
Used in Consumer Products:
This chemical can be found as an ingredient in a variety of consumer products, where it contributes to the performance, quality, or other attributes of these items.

InChI:InChI=1/C8H11NO4S/c1-12-6-3-4-7(13-2)8(5-6)14(9,10)11/h3-5H,1-2H3,(H2,9,10,11)

Upstream product

• 1483-28-9 2,5-dimethoxybenzene-1-sulfonyl chloride 
• 150-78-7 1,4-dimethoxybezene 

Downstream Products

• 28011-66-7 N-((2,5-dimethoxyphenyl)sulfonyl)acetamide 
• 128577-43-5 2-Cyclopentyl-N-{1-[4-(2,5-dimethoxy-benzenesulfonylaminocarbonyl)-2-methoxy-benzyl]-1H-indol-6-yl}-acetamide 
• 1057256-43-5 N-[2-(1H-Indol-4-yloxy)-acetyl]-2,5-dimethoxy-benzenesulfonamide 

Relevant academic research and scientific papers

N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase

Steroid sulfatase (STS) is an attractive target for a range of oestrogen- and androgen-dependent diseases. In search of novel chemotypes of STS inhibitors, we had previously identified nortropinyl-arylsulfonylureas 1; however, while these compounds were good inhibitors of purified STS (lowest Ki = 76 nM), they showed only weak inhibition of STS activity in cells (lowest IC50 around 2 μM). Extended structure-activity relationship studies involving modification of the phenylacetyl side chain and replacement of the nortropine element by simpler scaffolds led to the discovery of N-acyl arylsulfonamides, more specifically N-(Boc-piperidine-4-carbonyl)- benzenesulfonamides, as STS inhibitors, some of which exhibit improved cellular potency (best IC50 = 270 nM).

Herbicidal aryl triazolinones

Herbicidal aryl triazolinones include the compounds of the formula STR1 where X is preferably halogen such as fluorine, Y is preferably halogen such as chlorine, R1 is preferably methyl, R2 is preferably CHF2, R3/sup

Herbicidal aryl triazolinones

Herbicidal aryl triazolinones include the compounds of the formula STR1 where X is preferably halogen such as fluorine, Y is preferably halogen such as chlorine, R1 is preferably methyl, R2 is preferably CHF2, R3 is preferably CH(CH3), and STR2 is --NH2 or the residue of a primary or secondary amine or of a sulfonamide.