191168-70-4Relevant academic research and scientific papers
Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase
Kilic, Burcu,Gulcan, Hayrettin O.,Aksakal, Fatma,Ercetin, Tugba,Oruklu, Nihan,Umit Bagriacik,Dogruer, Deniz S.
, p. 235 - 249 (2018)
A series of new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring were designed, synthesized and evaluated for their ability to inhibit both cholinesterase enzymes. In addition, a series of carboxamide and propanamide derivat
Synthesis of 1-[ω-[(arylamino)carbonyl]alkyl]-4-(benzocycloalkyl)piperazines
El-Ahmad, Youssef,Maillet, Philippe,Laurent, Elisabeth,Talab, Akram,Tran, Gilles,Ollivier, Roland
, p. 723 - 734 (2007/10/03)
A series of 1-[co-[(arylamino)carbonyl]alkyl]-4-(benzocycloalkyl)-piperazines (1a-v) was prepared either by reacting the precursor 4-[ω-[(arylamino)carbonyl]alkyl]piperazine (2a-j) with 1-chlorobenzocycloalkanes (3a-c) (Procedure A) or by reacting the N-aryl-ω-chloroalkanamides (5a-j) with the 4-(benzocycloalkyl)piperazines (10a-c) (Procedure B). The best yields were obtained using procedure A.
