191222-10-3

Upstream product

• 191222-09-0 (1S,4S,8S)-8-((R)-2,2-Dimethyl-1-phenyl-propoxy)-6-methyl-2-oxa-bicyclo[2.2.2]oct-5-ene-4-carboxylic acid methyl ester 
• 191222-16-9 (1S,4S,8S)-8-((R)-2,2-Dimethyl-1-phenyl-propoxy)-6-methyl-3-oxo-2-oxa-bicyclo[2.2.2]oct-5-ene-4-carboxylic acid methyl ester 
• 191222-08-9 (1S,4S,6S)-6-((R)-2,2-Dimethyl-1-phenyl-propoxy)-4-hydroxy-1-hydroxymethyl-3-methyl-cyclohex-2-enecarboxylic acid methyl ester 

Downstream Products

• 191222-18-1 [(1R,6S)-6-((R)-2,2-Dimethyl-1-phenyl-propoxy)-1,3-dimethyl-2-phenylsulfanyl-cyclohex-3-enylmethoxy]-triisopropyl-silane 
• 191222-14-7 [(1R,6S)-6-((R)-2,2-Dimethyl-1-phenyl-propoxy)-1,3-dimethyl-4-phenylsulfanyl-cyclohex-2-enylmethoxy]-triisopropyl-silane 
• 191222-17-0 [(1R,6S)-6-((R)-2,2-Dimethyl-1-phenyl-propoxy)-1,3-dimethyl-2-phenylsulfanyl-cyclohex-3-enyl]-methanol 
• 191222-13-6 [(1R,6S)-6-((R)-2,2-Dimethyl-1-phenyl-propoxy)-1,3-dimethyl-4-phenylsulfanyl-cyclohex-2-enyl]-methanol 
• 191222-12-5 (1S,4R,8S)-8-((R)-2,2-Dimethyl-1-phenyl-propoxy)-4,6-dimethyl-2-oxa-bicyclo[2.2.2]oct-5-ene 
• 191222-11-4 (1S,4S,8S)-8-((R)-2,2-Dimethyl-1-phenyl-propoxy)-4-iodomethyl-6-methyl-2-oxa-bicyclo[2.2.2]oct-5-ene 

Relevant academic research and scientific papers

Diastereo- and enantioselective synthesis of allylsilane. A useful C-ring fragment of taxol

Enantioselective synthesis of a taxol C-ring fragment containing an allylsilane moiety is described. Diastereoselective [4 + 2] cycloaddition of the pyrone with (R)-t-butylbenzyl vinyl ether followed by appropriate transformations gave a mixture of two regioisomeric cyclohexenyl sulfides, which was converted It, the title compound with almost complete diastereo- and enantioselectivities by treating with Li and 4,4'-di-t-butylbiphenyl followed by quenching with chlorotrimethylsilane.