191222-62-5

Basic information

• Product Name: 3-Azabicyclo[3.1.0]hexane-2-thione,3-methyl-,(1S)-(9CI)
• Synonyms: 3-Azabicyclo[3.1.0]hexane-2-thione,3-methyl-,(1S)-(9CI)
• CAS NO: 191222-62-5
• Molecular Formula: C6H9NS
• Molecular Weight: 127.21
• Product Categories: AMINETERTIARY
• Mol File: 191222-62-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Azabicyclo[3.1.0]hexane-2-thione,3-methyl-,(1S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Azabicyclo[3.1.0]hexane-2-thione,3-methyl-,(1S)-(9CI)(191222-62-5)
• EPA Substance Registry System: 3-Azabicyclo[3.1.0]hexane-2-thione,3-methyl-,(1S)-(9CI)(191222-62-5)

Safety Data

• Hazardous Substances Data: 191222-62-5(Hazardous Substances Data)

Upstream product

• 155795-36-1 (1R,2S)-2-(1-methylethoxycarbonyl)-1-cyclopropanecarboxylic acid 
• 175275-35-1 (1S,5R)-3-methyl-3-azabicyclo[3.1.0]hexan-2-one 

Relevant articles and documents

Stereochemistry and chiroptical spectra of 3-azabicyclo[3.1.0]hexan-2-ones and thiones

Several optically active substituted 3-azabicyclo[3.1.0]hexan-2-ones and their thiocarbonyl analogues have been synthesized, and their circular dichroism spectra studied. The crystal structure of thiolactam la showed that the bicyclic skeleton of the title compounds assumes a sofa-like geometry. It is postulated that the cyclopropyl moiety and amide or thioamide group constitute an inherently chiral chromophore, helicity of which determines the Cotton effect sign corresponding to the n-π* electronic transition. The weak π-π* Cotton effect of thiolactams shows opposite sign to that observed for the lowest energy excitation.