1912400-29-3 Usage
General Description
3-(3-(Trifluoromethylthio)phenyl)-1H-pyrazol-5-amine is a complex organosulfur compound, characterized by a fluorine, sulfur, and nitrogen-rich structure. It contains a pyrazole ring, a type of unsaturated five-membered ring with two nitrogen atoms and three carbon atoms, substituted with an amine (-NH2) at the fifth position and a 3-(trifluoromethylthio)phenyl at the third position. Trifluoromethylthio is a functional group consisting of three fluorine atoms, one carbon atom, and a sulfur atom, known for resistance to metabolism and increasing lipophilicity. This chemical is used in various research fields including medicinal chemistry due to its unique reactive properties and may serve as a building block for various drug molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1912400-29-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,1,2,4,0 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1912400-29:
(9*1)+(8*9)+(7*1)+(6*2)+(5*4)+(4*0)+(3*0)+(2*2)+(1*9)=133
133 % 10 = 3
So 1912400-29-3 is a valid CAS Registry Number.
1912400-29-3Relevant articles and documents
ADMINISTRATION OF UBIQUITIN-ACTIVATING ENZYME INHIBITOR AND RADIATION
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Paragraph 0150-0151, (2016/05/19)
Disclosed are methods for the treatment of cancer in patients in need of such treatment. The methods comprise administering to such a patient an ubiquitin-activating enzyme (UAE) inhibitor such as ((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(trifluoromethylthio) phenyl)pyrazolo[1,5-a]pyrimidin-7-ylamino)cyclopentyl)methyl sulfamate (Compound 1) or a pharmaceutically acceptable salt in combination with radiation. Also disclosed are medicaments for use in the treatment of cancer.
