191283-22-4

Basic information

• Product Name: (S,S,S)-1,2-bis(2-methylphenyl)-2-hydroxyethyl (2-formyl-6,6-dimethyl-2-cyclohexen-1-yl)acetate
• Synonyms: (S,S,S)-1,2-bis(2-methylphenyl)-2-hydroxyethyl (2-formyl-6,6-dimethyl-2-cyclohexen-1-yl)acetate
• CAS NO: 191283-22-4
• Molecular Weight: 420.549
• Mol File: 191283-22-4.mol

Chemical Properties

• CAS DataBase Reference: (S,S,S)-1,2-bis(2-methylphenyl)-2-hydroxyethyl (2-formyl-6,6-dimethyl-2-cyclohexen-1-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (S,S,S)-1,2-bis(2-methylphenyl)-2-hydroxyethyl (2-formyl-6,6-dimethyl-2-cyclohexen-1-yl)acetate(191283-22-4)
• EPA Substance Registry System: (S,S,S)-1,2-bis(2-methylphenyl)-2-hydroxyethyl (2-formyl-6,6-dimethyl-2-cyclohexen-1-yl)acetate(191283-22-4)

Safety Data

• Hazardous Substances Data: 191283-22-4(Hazardous Substances Data)

Upstream product

• 191283-14-4 3,4,4a,5,6,7-hexahydro-5,5-dimethyl-4'S,5'S-bis(2-methylphenyl)spiro[8H-2-benzopyran-3,2'-[1,3]-dioxolan]-8-one 
• 253446-53-6 3,4,4a,5,6,7-hexahydro-5,5-dimethyl-4'S,5'S-bis(2-methylphenyl)spiro[8H-2-benzopyran-3,2'-[1,3]-dioxolan]-8-ol 

Downstream Products

• 172585-06-7 (S,S)-(+)-1,2-bis(2-methylphenyl)ethane-1,2-diol 
• 172277-06-4 (4S,5S)-2-Bromomethyl-4,5-di-o-tolyl-[1,3]dioxolane 

Relevant articles and documents

Stereo- and enantioselective routes to functionalised cyclohexenes via heterodiene cycloadditions of 6-oxocyclohexene-1-carbaldehydes with ketene acetals

Various substituted cyclohexenes related to α-cyclocitral have been prepared using the heterodiene cycloadditions of 2-formyl-4,4-dimethyl-2- cyclohexen-1-one 4 with ketene acetals as the pivotal step. The key intermediates are accessible in homochiral form via an auxiliary-based sequence in which a C2-symmetric ketene acetal derived from 1,2-bis(2- methylphenyl)ethane-1,2-diol 2a serves as the 2π component. The diol 2a can be recovered in optically pure form.

The use of homochiral 2-methylene-4,5-diaryl-1,3-dioxolanes as recyclable acetic ester enolate equivalents: asymetric synthesis of terpenoids

The α-cyclocitral derivatives 5 and 10 are accessible in homochiral form via an auxiliary-based sequence using the heterodiene cycloaddition of a 2-methylene-4,5-diaryl-1,3-dioxolane 1 to 2-formyl-4,4-dimethyl-2-cyclohexen-1-one 2 as the key step.