19130-39-3

Upstream product

• 13610-02-1 1-phenoxy-2-propyne 
• 244056-17-5 2-bromo-3-(4-chlorophenoxy)propene 
• 791590-30-2 2,3-dibromopropyl 4-chlorophenyl ether 
• 107-19-7 propargyl alcohol 
• 106-48-9 4-chloro-phenol 
• 344311-20-2 (4-chloro-phenoxy)-acetone semicarbazone 
• 6165-76-0 propargyl p-toluenesulfonate 
• 106-96-7 propargyl bromide 
• 85143-28-8 4-p-chlorophenoxymethyl-1,2,3-selenadiazole 

Downstream Products

• 139370-97-1 3-(4-chlorophenoxy)-2-phenylsulfinyl-1-propene 
• 108574-76-1 (1S,2S,4S)-2-[3-(4-Chloro-phenoxy)-prop-1-ynyl]-bicyclo[2.2.1]hept-5-en-2-ol 
• 16336-27-9 6-chloro-2H-chromene 
• 878-03-5 3-Jod-1-(4-chlor-phenoxy)-propin-⁽²⁾ 
• 17061-90-4 2,4-dichloro-1-(prop-2-yn-1-yloxy)benzene 
• 706-12-7 γ-bromopropargyl p-chlorophenyl ether 
• 117543-26-7 1-Chloro-4-(3-chloro-prop-2-ynyloxy)-benzene 
• 106-48-9 4-chloro-phenol 
• 940940-77-2 C₂₉H₂₇N₄SOCl 
• 37674-72-9 6-chloro-chroman-4-one 
• 1144040-29-8 4-(4-chloro-phenoxymethyl)-1-[2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl]-1H-[1,2,3]triazole 
• 1210938-00-3 4-[(4-chlorophenoxy)methyl]-α-phenyl-1H-1,2,3-triazole-1-ethanol 
• 1313994-68-1 1,3-bis-[4-(4-chloro-phenoxymethyl)-[1,2,3]triazol-1-yl]-propan-2-ol 
• 1322786-88-8 4-(4-chlorophenoxymethyl)-1-(tetrahydrofuran-2-ylmethyl)-1H-[1,2,3]triazole 

Relevant academic research and scientific papers

Preparation method and application of propyne aryl ether compound

The invention particularly relates to a method for preparing propyne aryl ether compounds from aryl phenol, halogenated propyne and derivatives of the halogenated propyne, and belongs to the technical field of preparation of the propyne aryl ether compoun

Synthesis of sorafenib analogues incorporating a 1,2,3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines

A series of 1,2,3-triazole-containing Sorafenib analogues, in which the aryl urea moiety of Sorafenib (1) was replaced with a 1,2,3-triazole ring linking a substituted phenoxy fragment, were prepared successfully via Huisgen 1,3-dipolar cycloaddition and

Enantioselective Palladium-Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine Oxides

A Pd-catalyzed hydrophosphinylation of alkyl and aryl-oxyallenes with phosphine oxides has been developed for the efficient and rapid construction of a family of chiral allylic phosphine oxides with a diverse range of functional groups. This methodology was further applied in the facile construction of chiral 2H-chromene and later stage functionalization of cholesterol.

Synthesis, characterization, PASS prediction and in silico ADME studies of ester and ether linked 1,4-disubstituted 1,2,3-triazoles derivatives via click approach

In the present investigation, we focused our interest on the synthesis of pharmacophoric units (quinoline and 1,2,3-triazole) linked through ester (3a-b) and (substituted aromatic ring and 1,2,3-triazole) linked through an ether (3c-h). The synthesis invo

Synthesis, characterization, and antiplasmodial efficacy of sulfonamide-appended [1,2,3]-triazoles

A series of benzenesulfonamide-appended [1,2,3]-triazole hybrids was synthesized by using [3 + 2] cycloaddition of primary, secondary, and tertiary sulfonamide azides with various phenoxymethylacetylenes under click reaction conditions. After structural c

Uniform copper nanoparticles as an inexpensive and efficient catalyst for synthesis of novel β-carbonyl-1, 2, 3-triazoles in water medium

Copper nanoparticles as an efficient, inexpensive catalyst were prepared via ball milling for synthesis of β-carbonyl 1, 2, 3-triazoles from azido alcohol by click reaction in water. An extensive range of raw materials such as sodium azide, phenacyl bromi

1,2,3-Triazole-based kojic acid analogs as potent tyrosinase inhibitors: Design, synthesis and biological evaluation

A series of kojic acid-derived compounds 6a-p bearing aryloxymethyl-1H-1,2,3-triazol-1-yl moiety were designed by modifying primary alcoholic group of kojic acid as tyrosinase inhibitors. The target compounds 6a-p were synthesized via click reaction. All

Preparation of novel 1,2,3-triazole furocoumarin derivatives via click chemistry and their anti-vitiligo activity

The extracts of Psoralea corylifolia?L. were often used for the repigmentation of leukoderma (vitiligo) in traditional Uygur medicine thousands years ago. Nowadays, its active ingredient, furocoumarins, has been clinically applied since it exhibited stron

Synthesis of 3-Organoselenyl-2H-Coumarins from Propargylic Aryl Ethers via Oxidative Radical Cyclization

A metal-free oxidative radical cyclization/selenylation of propargylic aryl ethers with diaryl diselenides was developed. This protocol provided an alternative method to synthesize 3-organoselenyl-2H-coumarins via the formation of C?Se bond, C?C bond, and C=O bond in one step. Moreover, a broad range of functional groups (such as halogen, aldehyde, ketone, cyano, and nitro group) were tolerated. (Figure presented.).

Gold(III)-Catalyzed Intermolecular Oxidation-Cyclization of Ynones: Access to 4-Substituted Chroman-3-ones

A synthesis of 4-substituted chroman-3-one derivatives has been developed through a gold(III) catalyzed oxidation-cyclization of ynones in good to excellent yield using easily prepared substrates. A broad range of synthetically useful functional groups (halide, alkene, alkyne, phenolic hydroxyl) were tolerated. Further application of this method paves a new way to prepare the skeleton of oblarotenoids. A cascade oxidative cyclization for construction of pyrano[2,3-c]chromen-1(5H)-one derivatives is also presented. (Figure presented.).