19133-00-7

Basic information

• Product Name: (2E)-1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
• Synonyms: (2E)-1-(4-Chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one; 2-propen-1-one, 1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]-, (2E)-; 4'-Chloro-4-dimethylaminochalcone
• CAS NO: 19133-00-7
• Molecular Formula: C₁₇H₁₆ClNO
• Molecular Weight: 285.768
• Mol File: 19133-00-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 451.6°C at 760 mmHg
• Flash Point: 226.9°C
• Density: 1.191g/cm³
• Vapor Pressure: 2.41E-08mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: (2E)-1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one(19133-00-7)
• EPA Substance Registry System: (2E)-1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one(19133-00-7)

Safety Data

• Hazardous Substances Data: 19133-00-7(Hazardous Substances Data)

Usage

General Description

The chemical "(2E)-1-(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one" is an organic compound that belongs to the family of prop-2-en-1-ones, also known as chalcones. It contains a 4-chlorophenyl group and a 4-(dimethylamino)phenyl group, with a prop-2-en-1-one backbone. Chalcones are known for their various biological activities, including anti-inflammatory, antitumor, antioxidant, and antimicrobial properties. This specific compound may have potential applications in pharmaceuticals, agrochemicals, and other industries due to its structural features and potential biological activities. Further research and testing are needed to fully understand its properties and potential uses.

Upstream product

• 101571-08-8 2,3-dibromo-1-(4-chloro-phenyl)-3-(4-dimethylamino-phenyl)-propan-1-one 
• 99-91-2 para-chloroacetophenone 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 101571-08-8 2,3-dibromo-1-(4-chloro-phenyl)-3-(4-dimethylamino-phenyl)-propan-1-one 
• 1606142-35-1 4-(4-chlorophenyl)-2-(4-(N,N-dimethylamino)phenyl)-2,3-dihydro-1,5-benzothiazepine 
• 590419-85-5 Pd[ClC₆H₄C(O)CHC(O)C₆H₄N(CH₃)2]2 
• 75573-12-5 {4-[2-(4-Chloro-phenyl)-6-p-tolyl-pyridin-4-yl]-phenyl}-dimethyl-amine 
• 123032-82-6 [(1R,2R)-2-(4-Chloro-benzoyl)-3-(4-dimethylamino-phenyl)-cyclopropyl]-(4-chloro-phenyl)-methanone 
• 123121-58-4 [(1R,2S,3S)-2-(4-Chloro-benzoyl)-3-(4-dimethylamino-phenyl)-cyclopropyl]-(4-chloro-phenyl)-methanone 
• 85460-64-6 [(1R,2S,3S)-2-Benzoyl-3-(4-dimethylamino-phenyl)-cyclopropyl]-(4-chloro-phenyl)-methanone 
• 85460-64-6 [(1R,2R,3S)-2-Benzoyl-3-(4-dimethylamino-phenyl)-cyclopropyl]-(4-chloro-phenyl)-methanone 
• 73910-97-1 4-[2,6-bis(4-chlorophenyl)pyridin-4-yl]-N,N-dimethylbenzenamine 

Relevant articles and documents

Pyrazoline analogs as potential anticancer agents and their apoptosis, molecular docking, MD simulation, DNA binding and antioxidant studies

N-formyl pyrazoline derivatives (3a–3l) were designed and synthesized via Michael addition reaction through cyclization of chalcones with hydrazine hydrate in presence of formic acid. The structural elucidation of N-formyl pyrazoline derivatives was carri

Novel benzothiazole based sulfonylureas/sulfonylthioureas: Design, synthesis and evaluation of their antidiabetic potential

In the present study, twenty-eight benzothiazole based sulfonylureas/sulfonylthioureas were synthesized and were assessed for their antidiabetic effect in a normoglycemic rat model by the in vivo oral glucose tolerance test (OGTT). All the synthesized com

Synthesis and evaluation of pyrazolines bearing benzothiazole as anti-inflammatory agents

The present study aims at the synthesis of pyrazolines bearing benzothiazole and their evaluation as anti-inflammatory agents. The synthesized compounds were evaluated for their anti-inflammatory potential using carrageenan induced paw edema model. Two co