191410-59-0Relevant academic research and scientific papers
Synthesis of chiral 1,3-diols by radical-mediated regioselective opening of 2,3-epoxy alcohols using cp2TiCl
Chakraborty, Tushar K,Das, Sanjib
, p. 2313 - 2315 (2007/10/03)
Radical-mediated opening of chiral 2,3-epoxy alcohols 1a-e, regioselectively at the 2-position, using cp2TiCl in the absence of a hydrogen source leads to the formation of the 1,3-diols 2a-e.
Regioselective Alkyl and Alkynyl Substitution Reactions of Epoxy Alcohols by the Use of Organoaluminum Ate Complexes: Regiochemical Reversal of Nucleophilic Substitution Reactions
Sasaki, Minoru,Tanino, Keiji,Miyashita, Masaaki
, p. 1765 - 1767 (2007/10/03)
(matrix presented) Unprecedented nucleophilic substitution reactions of 2,3-epoxy-1-alkanols with alkyl- and alkynylaluminum ate complexes have been studied and demonstrated to occur at the C2 position with extremely high stereoselectivity, i.e., with exa
Synthetic studies toward potent cytotoxic agents amphidinolides: Synthesis of the C1-C6 and C9-C17 moieties of amphidinolides O and P
Chakraborty,Das, Sanjib
, p. 80 - 81 (2007/10/03)
Stereoselective synthesis of the (4R)-C1-C6 and (14R, 15R)-C9-C17 segments, 4 and 5 respectively, of amphidinolides O and P have been achieved starting from a common chiral precursor 6 which was obtained by radical-mediated opening of a trisubstituted epoxy alcohol using Cp2TiCl-cyclohexa-1,4-diene.
Anti-Markovnikov opening of trisubstituted epoxy alcohols: Application in the synthesis of 2-methyl-1,3-diols
Chakraborty, Tushar K.,Dutta, Shantanu
, p. 1257 - 1259 (2007/10/03)
2-Methyl-1,3-diols are synthesized by regioselectively opening trisubstituted epoxides, prepared from 2-methylbut-2-en-1-ols at the more substituted carbon using Cp2TiCl-cyclohexa-1,4-diene.
