19146-45-3Relevant academic research and scientific papers
Characterization of a novel polysaccharide with anti-colon cancer activity from Lactobacillus helveticus MB2-1
Li, Wei,Tang, Weizhi,Ji, Juan,Xia, Xiudong,Rui, Xin,Chen, Xiaohong,Jiang, Mei,Zhou, Jianzhong,Dong, Mingsheng
, p. 6 - 14 (2015/05/13)
The present study aimed at investigating the potential anti-colon cancer activity of three purified exopolysaccharides fractions (LHEPS-1, LHEPS-2 and LHEPS-3) from the Lactobacillus helveticus MB2-1. The experimental evidence showed that LHEPS-1 significantly inhibited cell proliferation of human colon cancer Caco-2 cells in both time- and concentration-dependent manners. In contrast, no significant improvements of the inhibitory effects of LHEPS-2 and LHEPS-3 on Caco-2 cells were observed with increasing sample concentrations or prolonged incubation time. Furthermore, the structure of LHEPS-1 was elucidated using methylated analysis, gas chromatography-mass spectroscopy (GC-MS) and nuclear magnetic resonance spectroscopy (NMR), including one- and two-dimensional nuclear magnetic resonance (1D and 2D NMR). Results indicated that the LHEPS-1 consisted of a decasaccharide repeating unit with the following structure (n≈122): Our results suggested that the LHEPS-1 produced by L. helveticus MB2-1 might be suitable for using as natural anti-colon cancer drugs and functional foods ingredients.
A new flavonoidal constituent from taraxacum officinale (L.) weber
Yadava, Raj Nath,Khan, Shirin
, p. 4117 - 4118 (2013/06/05)
A new flavone glycoside (A) m.p. 265-268 °C, m.f. C33H 40O21, [M]+ 742 (FABMS), has been isolated from stem of Taraxacum oficinale (L.) Weber. It was characterized as 3,5,7,3',4'-pentahydroxy 8-C methyl flavone 7-O-β-D-xylopyranosyl (14)O-β-D glucopyranosyl 3'- O-α-L-rhamnopyranoside alongwith known compound ladanein B by various chemical degradations and spectral analysis.
