191476-01-4Relevant academic research and scientific papers
Synthesis and characterisation of α-carboxynitrobenzyl photocaged L-aspartates for applications in time-resolved structural biology
Zaitsev-Doyle, John J.,Puchert, Anke,Pfeifer, Yannik,Yan, Hao,Yorke, Briony A.,Müller-Werkmeister, Henrike M.,Uetrecht, Charlotte,Rehbein, Julia,Huse, Nils,Pearson, Arwen R.,Sans, Marta
, p. 8695 - 8699 (2019/03/21)
We report a new synthetic route to a series of α-carboxynitrobenzyl photocaged l-aspartates for application in time-resolved structural biology. The resulting compounds were characterised in terms of UV/Vis absorption properties, aqueous solubility and stability, and photocleavage rates (τ = μs to ms) and quantum yields (φ = 0.05 to 0.14).
Light-controlled DNA binding of bisbenzamidines
Sanchez, Mateo I.,Vazquez, Olalla,Vazquez, M. Eugenio,Mascarenas, Jose L.
, p. 11107 - 11109 (2011/11/12)
Caging of the amidinium moieties of two representative bisbenzamidine DNA binders with suitable photoresponsive protecting groups suppresses their DNA-binding, which can then be fully recovered upon irradiation with UV light that removes the caging groups
Non-photochemical rearrangements of o-nitrobenzyl compounds
Corrie, John E. T.,Gradwell, Michael J.,Papageorgiou, George
, p. 2977 - 2982 (2007/10/03)
Three rearrangements of 2-nitrobenzyl compounds with increasingly complex structural changes are described. The first is a remarkably facile conversion of 2-nitrobenzyl triflate to 2-nitrosobenzaldehyde. The second is an unexpected formation of 1-acetyl-2
Photolabile 'caged fatty acids containing a 1-(2'-nitrophenyl)-1,2-ethanediol moiety
Xia, Jie,Huang, Xupei,Sreekumar,Walker, Jeffery W.
, p. 1243 - 1248 (2007/10/03)
1-(2'-Nitrophenyl)ethanediol was used to esterify the carboxylic acid function of fatty acids to prepare photosensitive fatty acid precursors for biological studies. The synthesis, photochemistry, and biological properties of several model cis-unsaturated fatty acids including arachidonic acid are described.
